INT87714

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Context Info
Confidence 0.29
First Reported 2000
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.87
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ID1) cytoplasm (ID1)
Anatomy Link Frequency
A2780 2
ID1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 75.00 Quite High
COX2 1 25.00 Low Low
psoriasis 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 4 100.00 Very High Very High Very High
Aging 1 98.88 Very High Very High Very High
Ovarian Cancer 1 97.28 Very High Very High Very High
Psoriasis 5 91.24 High High
Colon Cancer 14 88.12 High High
INFLAMMATION 3 75.00 Quite High
Cancer 23 50.00 Quite Low
Skin Cancer 4 15.84 Low Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cell cycle blockade and differentiation caused by such a drug, trichostatin A, caused decreased levels of ID-1 consistent with cell cycle senescence and differentiation of A2780 ovarian cancer cells [17].
Positive_regulation (caused) of Negative_regulation (decreased) of ID-1 in A2780 associated with aging and ovarian cancer
1) Confidence 0.29 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1182358 Disease Relevance 0.29 Pain Relevance 0
Promoter studies indicated that c-Myb can activate COX-2 transcription, whereas dominant-negative Myb mediated repression.
Positive_regulation (mediated) of Negative_regulation (repression) of dominant-negative Myb associated with repression
2) Confidence 0.04 Published 2000 Journal Cancer Res. Section Abstract Doc Link 10766162 Disease Relevance 0.58 Pain Relevance 0.07

General Comments

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