INT8787

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Context Info
Confidence 0.42
First Reported 1992
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.42
Pain Relevance 1.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (WAS) protein complex assembly (WAS) cytoplasm (WAS)
Anatomy Link Frequency
blood vessels 1
Coronary sinus 1
WAS (Homo sapiens)
Pain Link Frequency Relevance Heat
Cannabinoid 96 100.00 Very High Very High Very High
agonist 38 100.00 Very High Very High Very High
Morphine 51 98.92 Very High Very High Very High
cannabis 46 97.66 Very High Very High Very High
Lasting pain 11 92.52 High High
adenocard 9 89.28 High High
Cluster headache 1 88.36 High High
Kappa opioid receptor 2 88.00 High High
Trigeminal neuralgia 1 87.56 High High
lidocaine 2 84.84 Quite High
Disease Link Frequency Relevance Heat
Cancer 98 99.48 Very High Very High Very High
Apoptosis 5 98.28 Very High Very High Very High
Nicotine Addiction 4 97.82 Very High Very High Very High
Death 1 97.76 Very High Very High Very High
Pain 59 92.52 High High
Cluster Headache 1 88.36 High High
Headache 3 87.56 High High
Poisoning 10 83.84 Quite High
Dizziness 3 64.88 Quite High
Vomiting 5 64.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Coronary sinus MB fraction of creatine kinase level was significantly decreased at 60 and 120 minutes of reperfusion in group II, as was mitochondrial aspartate aminotransferase level at 2 hours of reperfusion.
Negative_regulation (decreased) of was in Coronary sinus
1) Confidence 0.42 Published 1992 Journal J. Heart Lung Transplant. Section Abstract Doc Link 1379828 Disease Relevance 0 Pain Relevance 0.27
As more thoroughly reviewed elsewhere (Russo 2006b), cannabis smoking produces peak levels of serum THC above 140 ng/mL (Grotenhermen 2003; Huestis et al 1992), while comparable amounts of THC in Sativex administered oromucosally remained below 2 ng/mL (Guy and Robson 2003).


Negative_regulation (amounts) of THC associated with cannabis, nicotine addiction and agonist
2) Confidence 0.10 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2503660 Disease Relevance 0.84 Pain Relevance 0.67
Although morphine is not considered to be a psychedelic, and ibogaine, THC, and salvinorin A are not considered to be “classical hallucinogens,” these four compounds are included because they provide insights into additional receptor systems (salvinorin A – ?
Neg (not) Negative_regulation (considered) of THC associated with morphine
3) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2814854 Disease Relevance 0 Pain Relevance 0.49
Tumor vascularization was also impaired by cannabinoids, as both THC and JWH-133 decreased the number of blood vessels in the tumors, as determined by CD31 staining (Fig. 3C).
Negative_regulation (impaired) of THC in blood vessels associated with cancer and cannabinoid
4) Confidence 0.03 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2917429 Disease Relevance 1.59 Pain Relevance 0.38

General Comments

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