INT87985

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Context Info
Confidence 0.67
First Reported 2000
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.52
Pain Relevance 1.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (Dpagt1) endoplasmic reticulum (Dpagt1)
Anatomy Link Frequency
liver 1
Dpagt1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 1 100.00 Very High Very High Very High
Paracetamol 12 97.80 Very High Very High Very High
Inflammation 6 95.12 Very High Very High Very High
Analgesic 4 82.52 Quite High
Disease Link Frequency Relevance Heat
Arthritis 2 98.16 Very High Very High Very High
Toxicity 3 97.80 Very High Very High Very High
Injury 1 97.64 Very High Very High Very High
Granuloma 1 96.40 Very High Very High Very High
INFLAMMATION 6 95.12 Very High Very High Very High
Pressure And Volume Under Development 1 91.92 High High
Necrosis 1 87.44 High High
Hepatotoxicity 2 82.20 Quite High
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
P. niruri significantly reduced the elevated glutamate pyruvate transaminase (GPT) and alkaline phosphatase (ALP) levels in the sera of toxicity induced mice, compared with the control group.
Positive_regulation (elevated) of GPT associated with toxicity and glutamate
1) Confidence 0.67 Published 2006 Journal Phytother Res Section Abstract Doc Link 16718736 Disease Relevance 0.36 Pain Relevance 0.43
Solanum alatum treatment (100 mg/kg, p.o.) decreased the elevation of serum alanine aminotransferase (ALT; GPT) and aspartate aminotransferase (AST; GOT) induced by acetaminophen (paracetamol) (600 mg/kg, i.p.) administration.
Positive_regulation (elevation) of GPT associated with paracetamol
2) Confidence 0.45 Published 2000 Journal Am. J. Chin. Med. Section Abstract Doc Link 10794122 Disease Relevance 0.26 Pain Relevance 0.45
Further, the product inhibited the increased level of serum lysosomal enzyme activity viz. serum glutamic oxaloacetic transaminase, serum glutamic pyruvic transaminase, alkaline phosphatase and the lipid peroxidation in liver.
Positive_regulation (increased) of serum lysosomal enzyme in liver
3) Confidence 0.01 Published 2007 Journal Indian J. Exp. Biol. Section Abstract Doc Link 17373374 Disease Relevance 0.89 Pain Relevance 0.49

General Comments

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