INT88000

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Context Info
Confidence 0.55
First Reported 2000
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 15
Total Number 16
Disease Relevance 6.94
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
blood 1
gut 1
LAP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 71 95.76 Very High Very High Very High
abdominal pain 8 92.64 High High
backache 1 92.20 High High
Inflammatory response 60 91.48 High High
alcohol 2 87.60 High High
aspirin 29 81.12 Quite High
cINOD 89 71.64 Quite High
cytokine 26 49.04 Quite Low
chemokine 15 47.92 Quite Low
Cholecystokinin 15 25.12 Quite Low
Disease Link Frequency Relevance Heat
Obesity 80 100.00 Very High Very High Very High
Lymphadenopathy 10 100.00 Very High Very High Very High
Abscess 2 100.00 Very High Very High Very High
Cardiovascular Disease 205 99.80 Very High Very High Very High
Pressure And Volume Under Development 19 98.96 Very High Very High Very High
INFLAMMATION 147 95.76 Very High Very High Very High
Disease 66 94.12 High High
Abdominal Pain 8 92.64 High High
Low Back Pain 1 92.20 High High
Weight Loss 13 91.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Figures 1, 2, 3, 4, 5, 6, 7, and 8 represent the sex-specific Kaplan-Meier curves for CVD and all-cause mortality, across LAP quartiles in the two sub-groups defined by baseline global CVD risk ?
Gene_expression (quartiles) of LAP associated with cardiovascular disease
1) Confidence 0.55 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2949857 Disease Relevance 0.91 Pain Relevance 0
In the analysis of CVD outcome, LAP, BMI, WHpR, and WHtR were assessed using Cox proportional hazards regression analyses.
Gene_expression (assessed) of LAP associated with cardiovascular disease and obesity
2) Confidence 0.55 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2949857 Disease Relevance 1.19 Pain Relevance 0
Perforations present in the LAP and LIPUS+LAP undecalcified slides filled to varying degrees with immature woven bone after 4 months of healing.
Gene_expression (present) of LAP
3) Confidence 0.55 Published 2008 Journal J Orthop Surg Section Body Doc Link PMC2414658 Disease Relevance 0.26 Pain Relevance 0.05
REVIEWER'S CONCLUSIONS: The results of one small trial showed that ligation and LAP produced a moderate improvement for two years after surgery, in patients with mild to moderate DVI caused by primary valvular incompetence.
Gene_expression (produced) of LAP
4) Confidence 0.50 Published 2000 Journal Cochrane Database Syst Rev Section Body Doc Link 10796592 Disease Relevance 0 Pain Relevance 0
Perforations present in the LAP and LIPUS+LAP undecalcified slides filled to varying degrees with immature woven bone after 4 months of healing.
Gene_expression (present) of LAP
5) Confidence 0.48 Published 2008 Journal J Orthop Surg Section Body Doc Link PMC2414658 Disease Relevance 0.26 Pain Relevance 0.05
Ligation and LAP produced significant improvement in AVP: the mean difference between the Ligation and LAP group and the Ligation only group was -15 torr (weighted mean difference [WMD] -20.9, -9.0, confidence interval [CI] 95% fixed) at one year and -15 torr (WMD -21, -8.9, 95% CI fixed) at two years.
Gene_expression (produced) of LAP
6) Confidence 0.34 Published 2000 Journal Cochrane Database Syst Rev Section Body Doc Link 10796592 Disease Relevance 0 Pain Relevance 0
HTS and LAP collected the data.
Gene_expression (collected) of LAP
7) Confidence 0.29 Published 2010 Journal Breast Cancer Res Section Body Doc Link PMC2879557 Disease Relevance 0.26 Pain Relevance 0.42
HTS and LAP collected the data.
Gene_expression (collected) of LAP
8) Confidence 0.22 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2656898 Disease Relevance 0.74 Pain Relevance 0
On abdominal CT, besides ascites, gut wall thickness (frequently ileocecal region), LAP, abscess, and organomegaly etc. were detected in 81.8%.
Gene_expression (detected) of LAP in gut associated with pressure and volume under development, lymphadenopathy and abscess
9) Confidence 0.15 Published 2005 Journal BMC Gastroenterol Section Body Doc Link PMC1183200 Disease Relevance 1.53 Pain Relevance 0.16
The subculture on blood agar media showed a small, alpha-hemolytic colony, catalase and oxidase negative, PYR and LAP positive and the production of H2S in triple sugar iron agar, was demonstrated.
Neg (negative) Gene_expression (negative) of LAP in blood
10) Confidence 0.08 Published 2005 Journal Rev. Argent. Microbiol. Section Abstract Doc Link 16178460 Disease Relevance 0.92 Pain Relevance 0.14
Western blot analysis using the C-terminal specific c/ebp Beta antibody showed that the levels of both the LAP and LIP isoforms of c/ebp Beta were increased after treatment with LPS, in accordance with a previous report (14) (Figure 3).
Gene_expression (levels) of LAP
11) Confidence 0.07 Published 2009 Journal Nucleic Acids Research Section Body Doc Link PMC2761263 Disease Relevance 0.26 Pain Relevance 0
The splenocytes of untreated mice showed low levels of c/ebp Beta proteins, whereas the levels of both the LAP and LIP isoform of c/ebp Beta were significantly increased 24 h after treatment with LPS (Figure 4C), in accordance with a previous report (14).
Gene_expression (levels) of LAP
12) Confidence 0.07 Published 2009 Journal Nucleic Acids Research Section Body Doc Link PMC2761263 Disease Relevance 0.05 Pain Relevance 0.03
This resulted in significant derepression of both the LAP and LIP isoforms in comparison to the vehicle-treated control mice (Figure 4C), which is consistent with the notion that miR-155 negatively regulates c/ebp Beta proteins in vivo in mouse splenocytes during acute inflammatory response.
Gene_expression (derepression) of LAP associated with inflammatory response
13) Confidence 0.06 Published 2009 Journal Nucleic Acids Research Section Body Doc Link PMC2761263 Disease Relevance 0.09 Pain Relevance 0.05
Western blot analysis using the C-terminal specific c/ebp Beta antibody showed that the levels of both the LAP and LIP isoforms of c/ebp Beta were increased after treatment with LPS, in accordance with a previous report (14) (Figure 3).
Gene_expression (isoforms) of LAP
14) Confidence 0.06 Published 2009 Journal Nucleic Acids Research Section Body Doc Link PMC2761263 Disease Relevance 0.25 Pain Relevance 0
(C) Western blot analysis of the c/ebp Beta LAP and LIP isoforms in splenocytes of mice treated with saline (n = 3), LNA-antimiR (n = 5) or LNA control (n = 5) by three intravenous injections of 25 mg/kg over three consecutive days.
Gene_expression (isoforms) of LAP
15) Confidence 0.06 Published 2009 Journal Nucleic Acids Research Section Body Doc Link PMC2761263 Disease Relevance 0.12 Pain Relevance 0.03
The fecal energy content of DS rats was higher than that of control LAP rats (20411.15?
Gene_expression (rats) of LAP
16) Confidence 0.04 Published 2010 Journal J Gastrointest Surg Section Body Doc Link PMC2943575 Disease Relevance 0.09 Pain Relevance 0

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