INT88024

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Context Info
Confidence 0.50
First Reported 2000
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.19
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ifng, Faslg) extracellular region (Ifng, Faslg) signal transduction (Faslg)
cytoplasmic membrane-bounded vesicle (Faslg) plasma membrane (Faslg)
Ifng (Rattus norvegicus)
Faslg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 1 98.52 Very High Very High Very High
tolerance 18 92.40 High High
Inflammation 4 75.16 Quite High
Sciatic nerve 1 56.24 Quite High
Neuritis 1 50.72 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 1 92.12 High High
Cancer 1 91.76 High High
Apoptosis 19 84.52 Quite High
INFLAMMATION 4 75.16 Quite High
Malignant Neoplastic Disease 1 72.40 Quite High
Brain Tumor 1 69.52 Quite High
Experimental Autoimmune Neuritis 1 52.64 Quite High
Liver Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IFN-gamma induced overexpression of FasL in KC has been proposed as a mechanism of hepatic immunoregulation [17].
IFN-gamma Positive_regulation (induced) of Gene_expression (overexpression) of FasL
1) Confidence 0.50 Published 2004 Journal Comp Hepatol Section Body Doc Link PMC2410251 Disease Relevance 0.21 Pain Relevance 0.17
IFN-gamma induced overexpression of FasL in KC has been proposed as a mechanism of hepatic immunoregulation [17].
IFN-gamma Positive_regulation (overexpression) of Gene_expression (overexpression) of FasL
2) Confidence 0.50 Published 2004 Journal Comp Hepatol Section Body Doc Link PMC2410251 Disease Relevance 0.21 Pain Relevance 0.17
IFN-gamma and TNF-alpha acted synergistically, leading to an increased FasL expression that reached its maximum 70 h after cytokine exposure, as shown by FACS analysis, SDS-PAGE, and Western blot.
IFN-gamma Positive_regulation (leading) of Gene_expression (expression) of FasL associated with cytokine
3) Confidence 0.28 Published 2000 Journal Glia Section Abstract Doc Link 10797617 Disease Relevance 0.76 Pain Relevance 0.20

General Comments

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