INT88070

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Context Info
Confidence 0.18
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 7.39
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
multinucleated giant cells 2
Ema (Mus musculus)
Pain Link Frequency Relevance Heat
nud 1 82.32 Quite High
abdominal pain 9 73.40 Quite High
spastic colon 1 66.48 Quite High
peripheral neuropathy 1 58.64 Quite High
Central nervous system 2 54.40 Quite High
Pain 4 34.44 Quite Low
Spinal cord 1 10.64 Low Low
Crohn's disease 1 9.20 Low Low
Inflammation 6 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rhabdomyosarcoma 2 99.32 Very High Very High Very High
Nerve Sheath Neoplasms 7 98.52 Very High Very High Very High
Cancer 116 98.08 Very High Very High Very High
Hyperplasia 6 98.08 Very High Very High Very High
Leiomyosarcoma 2 97.20 Very High Very High Very High
Meningioma 10 97.04 Very High Very High Very High
Sarcoma 33 96.56 Very High Very High Very High
Celiac Disease 103 95.60 Very High Very High Very High
Disease 124 94.96 High High
Anaplastic Large Cell Lymphoma 23 92.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A whorled growth pattern and psammoma bodies, combined with positive EMA and vimentin immunohistochemical reactions, can confirm the diagnosis of meningioma.
EMA Binding (combined) of associated with meningioma
1) Confidence 0.18 Published 2000 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 10800982 Disease Relevance 1.35 Pain Relevance 0.03
Immunohistochemically, the multinucleated giant cells were positive for vimentin, CD68 and CD45, and negative for cytokeratin and epithelial membrane antigen (EMA).
EMA Binding (cytokeratin) of in multinucleated giant cells
2) Confidence 0.09 Published 2009 Journal Pathol. Oncol. Res. Section Abstract Doc Link 18493871 Disease Relevance 0.67 Pain Relevance 0.07
Immunohistochemically, the multinucleated giant cells were positive for vimentin, CD68 and CD45, and negative for cytokeratin and epithelial membrane antigen (EMA).
EMA Binding (negative) of in multinucleated giant cells
3) Confidence 0.09 Published 2009 Journal Pathol. Oncol. Res. Section Abstract Doc Link 18493871 Disease Relevance 0.68 Pain Relevance 0.07
Based on a series of 41 patients, Weinberg et al. conclude that immunostaining with CD30, EMA, ALK1, and granzyme has only minor additional value above H&E staining [73].
EMA Binding (immunostaining) of
4) Confidence 0.08 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 0.46 Pain Relevance 0
However positivity for EMA and CK helps for a correct diagnosis.
EMA Binding (positivity) of
5) Confidence 0.07 Published 2006 Journal Cytojournal Section Body Doc Link PMC1562442 Disease Relevance 0.84 Pain Relevance 0
This patient however was not tested for anti-tTG at the time of diagnosis but did have positive EMA and AGA.
EMA Binding (positive) of
6) Confidence 0.06 Published 2006 Journal Nutr J Section Body Doc Link PMC1574337 Disease Relevance 1.42 Pain Relevance 0.14
Possibility of an epithelioid rhabdomyosarcoma was discarded considering strong immunoreactvity for CK, CK7 and EMA along with Myo D-1 negativity.
EMA Binding (immunoreactvity) of associated with rhabdomyosarcoma
7) Confidence 0.03 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1820783 Disease Relevance 1.98 Pain Relevance 0

General Comments

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