INT88080

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Context Info
Confidence 0.03
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Psmb6) signal transduction (Chrna4) transport (Chrna4)
nucleus (Psmb6) plasma membrane (Chrna4) neurological system process (Chrna4)
Chrna4 (Mus musculus)
Psmb6 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 2 98.24 Very High Very High Very High
Antinociceptive 2 97.08 Very High Very High Very High
Nicotine 2 96.04 Very High Very High Very High
Dopamine 1 93.32 High High
Central nervous system 1 88.20 High High
Hippocampus 1 86.64 High High
Disease Link Frequency Relevance Heat
Dementia 1 99.52 Very High Very High Very High
Pain 2 98.24 Very High Very High Very High
Cognitive Disorder 1 91.72 High High
Targeted Disruption 1 75.00 Quite High
Convulsion 1 72.24 Quite High
Epilepsy 1 68.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The alpha 4 nAChR is associated mainly with the beta 2 subunit, and may form a component of the nicotinic pain pathways modulating the antinociceptive effect of nicotine.
4 nAChR Binding (associated) of 2 subunit associated with pain, nicotine and antinociceptive
1) Confidence 0.03 Published 1999 Journal Nihon Shinkei Seishin Yakurigaku Zasshi Section Abstract Doc Link 10803206 Disease Relevance 0.56 Pain Relevance 0.46

General Comments

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