INT88140

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Context Info
Confidence 0.05
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.18
Pain Relevance 2.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (1700061J05Rik) cellular_component (1700061J05Rik) biological_process (1700061J05Rik)
1700061J05Rik (Mus musculus)
Pain Link Frequency Relevance Heat
Neuritis 56 100.00 Very High Very High Very High
Demyelination 4 96.72 Very High Very High Very High
Inflammation 24 95.32 Very High Very High Very High
Sciatic nerve 3 92.76 High High
peripheral neuropathy 1 86.88 High High
Peripheral nervous system 10 52.96 Quite High
cytokine 26 40.40 Quite Low
Multiple sclerosis 10 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 56 100.00 Very High Very High Very High
Demyelinating Disease 4 96.72 Very High Very High Very High
INFLAMMATION 26 95.32 Very High Very High Very High
Disease 16 85.72 High High
Syndrome 38 77.44 Quite High
Immunization 5 75.44 Quite High
Bordatella Infection 2 75.00 Quite High
Targeted Disruption 38 69.92 Quite High
Sprains And Strains 2 60.60 Quite High
Autoimmune Disease 14 52.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moderate to severe EAN can be induced in SJL/J mice by the injection of a combination of BPNM in CFA and PT.
Positive_regulation (induced) of EAN associated with neuritis
1) Confidence 0.05 Published 2000 Journal J. Neuroimmunol. Section Abstract Doc Link 10808045 Disease Relevance 1.11 Pain Relevance 0.82
And apoE-deficient mice were shown to suffer impaired BNB and BBB, which might be one of the reasons why apoE-deficient mice underwent more severe EAN [132, 133].
Positive_regulation (underwent) of EAN associated with neuritis
2) Confidence 0.02 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2825561 Disease Relevance 1.08 Pain Relevance 0.66
Previously, we explored the role of apoE in P0 peptide 180–199 induced EAN.
Positive_regulation (induced) of EAN associated with neuritis
3) Confidence 0.02 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2825561 Disease Relevance 0.99 Pain Relevance 0.70

General Comments

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