INT88238

Context Info Confidence 0.03 First Reported 2000 Last Reported 2000 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.27 Pain Relevance 0.10

plasma membrane (HLA-B)

HLA-B (Homo sapiens) Gbp1 (Mus musculus)

Pain Link Frequency Relevance Heat spinal inflammation 1 98.36

Disease Link Frequency Relevance Heat Ankylosis 2 100.00 Low Back Pain 1 98.36

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

OBJECTIVE: To investigate whether HLA-B27 influences the expression of murine progressive ankylosis (MPA), a single-gene autosomal recessive mouse model of ankylosing spondylitis that arises in mice homozygous for the ank gene.

HLA-B27 Spec (whether) Regulation (influences) of Gene_expression (expression) of MPA associated with spinal inflammation and ankylosis

1) Confidence 0.03 Published 2000 Journal J. Rheumatol. Section Abstract Doc Link 10813297 Disease Relevance 0.27 Pain Relevance 0.10

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