INT88374

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Context Info
Confidence 0.75
First Reported 2000
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.20
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (DPP3) nucleolus (DPP3) plasma membrane (DPP3)
nucleus (DPP3) cytoplasm (DPP3)
DPP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 3 95.96 Very High Very High Very High
Enkephalin 2 79.84 Quite High
alcohol 2 65.12 Quite High
Spinal cord 1 51.12 Quite High
Arthritis 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 1 98.60 Very High Very High Very High
Pain 3 95.96 Very High Very High Very High
Malignant Neoplastic Disease 2 73.80 Quite High
Liver Disease 2 73.24 Quite High
Diabetes Mellitus 2 68.80 Quite High
Infection 12 58.92 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 6 58.48 Quite High
Pleural Effusion 2 56.64 Quite High
Sprains And Strains 24 54.32 Quite High
Emaciation 2 36.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we report the heterologous expression of human DPP III and the site-directed mutagenesis results which demonstrate a functional role for Tyr318 at the active site of this enzyme.
Gene_expression (expression) of DPP III
1) Confidence 0.75 Published 2008 Journal Biol. Chem. Section Abstract Doc Link 18163885 Disease Relevance 0.19 Pain Relevance 0.10
These results indicated that tynorphin had a more effective structure for expression of inhibitory activity toward DPPIII.
Gene_expression (expression) of DPPIII
2) Confidence 0.50 Published 2000 Journal Peptides Section Abstract Doc Link 10822105 Disease Relevance 0 Pain Relevance 0.16
Firstly, physiologic tests realized in the API corynesystem (bioMérieux-F) strips were catalase positive, showed a positive reaction for pyrazinamidase, pyrolidonyl arylamidase, alkaline phosphatase, and acid production from glucose and maltose, were negative for oxydase, nitrate reduction, and urease.
Gene_expression (production) of arylamidase
3) Confidence 0.01 Published 2010 Journal BMC Infect Dis Section Body Doc Link PMC3009641 Disease Relevance 0.50 Pain Relevance 0.03
Firstly, physiologic tests realized in the API corynesystem (bioMérieux-F) strips were catalase positive, showed a positive reaction for pyrazinamidase, pyrolidonyl arylamidase, alkaline phosphatase, and acid production from glucose and maltose, were negative for oxydase, nitrate reduction, and urease.
Neg (negative) Gene_expression (negative) of arylamidase
4) Confidence 0.01 Published 2010 Journal BMC Infect Dis Section Body Doc Link PMC3009641 Disease Relevance 0.50 Pain Relevance 0.03

General Comments

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