INT88453

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Context Info
Confidence 0.33
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.48
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Uncx)
Uncx (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 10 95.88 Very High Very High Very High
midbrain 2 95.44 Very High Very High Very High
Hippocampus 2 94.64 High High
Enkephalin 4 25.00 Low Low
isoflurane 8 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 88 99.32 Very High Very High Very High
Cancer 4 90.72 High High
Sprains And Strains 152 68.32 Quite High
Hyperoxia 220 67.64 Quite High
Fatigue 1 63.44 Quite High
Ocular Toxicity (including Many Sub-types) 108 62.60 Quite High
Smear Layer 16 25.20 Quite Low
Retinal Neovascularization 4 5.92 Low Low
Cv General 2 Under Development 1 5.80 Low Low
Retinopathy 36 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of PHD1 remained unchanged or significantly decreased upon exposure to hypoxia.
Gene_expression (Expression) of PHD1 associated with hypoxia
1) Confidence 0.33 Published 2009 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2821581 Disease Relevance 1.06 Pain Relevance 0
There are three prolyl hydroxylases: PHD1, PHD2, and PHD3, all of which have been shown to have different functions in regulating HIF-1?
Gene_expression (three) of PHD1
2) Confidence 0.29 Published 2009 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2821581 Disease Relevance 1.36 Pain Relevance 0
To investigate the factors involved in CHX-induced proENK and TH mRNA expression, the effect of CHX on activator protein-1 (AP-1), cAMP response element (CRE) binding protein (CREB), and glucocorticoid response element (GRE) was tested.
Gene_expression (expression) of CHX-induced
3) Confidence 0.13 Published 2000 Journal Mol. Pharmacol. Section Abstract Doc Link 10825388 Disease Relevance 0 Pain Relevance 0.21
The pretreatment with actinomycin D (0.5 mg/kg) significantly decreased CHX-induced proENK and TH mRNA expression, suggesting that the CHX-dependent increase of these mRNA levels may be caused by the increase of transcriptional activity rather than RNA stabilization.
Gene_expression (expression) of CHX-induced
4) Confidence 0.13 Published 2000 Journal Mol. Pharmacol. Section Abstract Doc Link 10825388 Disease Relevance 0 Pain Relevance 0.21
PCA is the main product of the interaction of NaOCl and CHX, and has the molecular formula NaC6H4Cl.[36] When mixed with NaOCl, CHX molecules become hydrolyzed into smaller fragments, each forming a byproduct.
Gene_expression (product) of CHX
5) Confidence 0.01 Published 2010 Journal Journal of Conservative Dentistry : JCD Section Body Doc Link PMC3010032 Disease Relevance 0.06 Pain Relevance 0

General Comments

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