INT88759

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Context Info
Confidence 0.41
First Reported 2000
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.65
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (A1CF) endoplasmic reticulum (A1CF) intracellular (A1CF)
cytoplasm (A1CF) mRNA binding (A1CF) RNA binding (A1CF)
Anatomy Link Frequency
body 1
A1CF (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 8 98.78 Very High Very High Very High
aspirin 1 68.36 Quite High
cINOD 2 67.60 Quite High
Disease Link Frequency Relevance Heat
Aberrant Crypt Foci 9 100.00 Very High Very High Very High
Body Weight 1 98.56 Very High Very High Very High
Intestinal Cancer 4 97.04 Very High Very High Very High
Colon Cancer 4 75.84 Quite High
Polyps 1 72.52 Quite High
INFLAMMATION 1 67.04 Quite High
Adenocarcinoma 2 46.24 Quite Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BSZ treatment of AOM-injected rats reduced ACF formation in a dose-dependent manner by 60% with the greatest effect observed on ACF with 4 or more crypts.
Negative_regulation (reduced) of ACF associated with aberrant crypt foci
1) Confidence 0.41 Published 2000 Journal Int. J. Oncol. Section Abstract Doc Link 10853036 Disease Relevance 1.17 Pain Relevance 0.17
In an aberrant crypt foci (ACF) bioassay, feeding of capsaicin and rotenone at a dose of 500 ppm for 4 weeks significantly inhibited ACF formation induced by AOM (20 mg/kg body weight, once a week for 2 weeks).
Negative_regulation (inhibited) of ACF in body associated with aberrant crypt foci, body weight and qutenza
2) Confidence 0.41 Published 2001 Journal Int. J. Oncol. Section Abstract Doc Link 11604990 Disease Relevance 0.48 Pain Relevance 0.46

General Comments

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