INT88814

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Context Info
Confidence 0.14
First Reported 2000
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.35
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TTPA) transport (TTPA) intracellular (TTPA)
lipid metabolic process (TTPA) cytoplasm (TTPA)
Anatomy Link Frequency
visceral 1
plasma 1
TTPA (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 13 97.20 Very High Very High Very High
rheumatoid arthritis 54 5.00 Very Low Very Low Very Low
Inflammation 21 5.00 Very Low Very Low Very Low
corticosteroid 6 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 13 98.56 Very High Very High Very High
Metastasis 20 97.28 Very High Very High Very High
Cv General 3 Under Development 11 97.20 Very High Very High Very High
Cancer 33 94.12 High High
Non-small-cell Lung Cancer 38 93.88 High High
Bronchiolo-alveolar Adenocarcinoma 5 85.20 High High
Stress 15 75.00 Quite High
Angina 2 69.16 Quite High
Disease 68 66.80 Quite High
Coronary Artery Disease 3 57.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A supportive multivariate analysis of ORR, adjusted for the same covariates as used for the TTP analysis, showed that prior adjuvant tamoxifen, as well as visceral or bone metastases as the dominant site of metastases, significantly decreased the probability of achieving a response.
Gene_expression (analysis) of TTP in visceral associated with metastasis
1) Confidence 0.14 Published 2007 Journal Breast Cancer Res Treat Section Body Doc Link PMC2001219 Disease Relevance 0.26 Pain Relevance 0
EGFR gene amplification and a high polysomy was associated better response, TTP and OS (18.7 months vs 7 months).
Gene_expression (response) of TTP
2) Confidence 0.07 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721286 Disease Relevance 0.40 Pain Relevance 0
There was no significant difference in plasma levels of alpha-tocopherol, vitamin C, alpha- and beta-carotene.
Gene_expression (levels) of alpha-tocopherol in plasma
3) Confidence 0.02 Published 2000 Journal Atherosclerosis Section Abstract Doc Link 10856533 Disease Relevance 1.23 Pain Relevance 0.76
-tocopherol was expressed in relation to p-triglycerides the changes from baseline did not reach statistical significance (p = 0.133).
Gene_expression (expressed) of tocopherol
4) Confidence 0.01 Published 2003 Journal Nutr J Section Body Doc Link PMC194256 Disease Relevance 0.14 Pain Relevance 0
For this reason we expressed the tocopherol levels as the ratio of tocopherol:(total cholesterol+triglycerides) as proposed by Turnham et al [26].
Gene_expression (expressed) of tocopherol associated with disorder of lipid metabolism
5) Confidence 0.01 Published 2003 Journal Nutr J Section Body Doc Link PMC194256 Disease Relevance 0.34 Pain Relevance 0

General Comments

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