INT88883

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Context Info
Confidence 0.11
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.53
Pain Relevance 2.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6, Nfkb1) nucleus (IRF6, Nfkb1) DNA binding (IRF6, Nfkb1)
cytoplasm (IRF6, Nfkb1) signal transduction (Nfkb1) mitochondrion (Nfkb1)
IRF6 (Homo sapiens)
Nfkb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 18 98.64 Very High Very High Very High
aspirin 6 86.72 High High
Inflammation 8 76.08 Quite High
Analgesic 4 64.08 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 8 76.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acetaminophen inhibited iNOS mRNA expression, promoter activity of iNOS gene and nuclear factor-kappa B (NF-kappaB) binding activity induced by LPS plus IFN-gamma, whereas salicylates did not show any effect on them.
LPS Positive_regulation (induced) of nuclear factor-kappa B associated with paracetamol
1) Confidence 0.11 Published 2000 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 10860828 Disease Relevance 0.27 Pain Relevance 1.01
Acetaminophen inhibited iNOS mRNA expression, promoter activity of iNOS gene and nuclear factor-kappa B (NF-kappaB) binding activity induced by LPS plus IFN-gamma, whereas salicylates did not show any effect on them.
LPS Positive_regulation (induced) of NF-kappaB associated with paracetamol
2) Confidence 0.10 Published 2000 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 10860828 Disease Relevance 0.26 Pain Relevance 1.00

General Comments

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