INT88924

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Context Info
Confidence 0.41
First Reported 2000
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.77
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (FAP) extracellular space (FAP) plasma membrane (FAP)
FAP (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 96.04 Very High Very High Very High
cINOD 2 51.60 Quite High
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 8 100.00 Very High Very High Very High
Polyps 5 99.96 Very High Very High Very High
Cancer 5 99.60 Very High Very High Very High
Colon Cancer 3 88.60 High High
Carcinoma 1 65.20 Quite High
Adenoma 2 64.64 Quite High
INFLAMMATION 1 51.04 Quite High
Adenomatous Polyps 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Adduct levels in colonic epithelia decreased in the order: FAP polyps > tumor-adjacent tissue > tumor, normal and tumor-distal tissue.
Negative_regulation (decreased) of FAP associated with cancer, familial adenomatous polyposis and polyps
1) Confidence 0.41 Published 2000 Journal Int. J. Cancer Section Abstract Doc Link 10861445 Disease Relevance 1.77 Pain Relevance 0.10
In this paper, we report an inhibitory effect of these peptides on dipeptidyl peptidase IV (DPPIV) activity, known to be involved in regulatory functions such as the activation or inactivation of peptides.
Negative_regulation (effect) of DPPIV
2) Confidence 0.03 Published 2004 Journal Biochimie Section Abstract Doc Link 14987798 Disease Relevance 0 Pain Relevance 0.10

General Comments

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