INT89067

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Context Info
Confidence 0.31
First Reported 2000
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.84
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sema3a) extracellular space (Sema3a) extracellular region (Sema3a)
Anatomy Link Frequency
spinal cords 2
peripheral nervous systems 2
Sema3a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropathic pain 1 98.60 Very High Very High Very High
Dorsal horn 1 94.20 High High
Lasting pain 1 86.04 High High
Spinal cord 4 82.80 Quite High
dorsal root ganglion 1 81.60 Quite High
Calcitonin gene-related peptide 1 80.16 Quite High
substance P 1 77.28 Quite High
Nerve growth factor 1 75.00 Quite High
Sciatic nerve 3 71.92 Quite High
dorsal rhizotomy 1 69.68 Quite High
Disease Link Frequency Relevance Heat
Injury 1 98.88 Very High Very High Very High
Neuropathic Pain 2 98.60 Very High Very High Very High
Nervous System Malformation 1 92.64 High High
Nociception 4 91.32 High High
Pain 2 86.04 High High
Ganglion Cysts 1 80.64 Quite High
Frailty 1 79.96 Quite High
Hyperalgesia 1 37.68 Quite Low
Nervous System Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The chemorepulsive effect of virus-mediated semaphorin3A expression was shown to counteract the sprouting induced by NGF in a dose-dependent manner, both in vitro and in adult rat spinal cords.
Regulation (effect) of Gene_expression (expression) of semaphorin3A in spinal cords
1) Confidence 0.31 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 14749426 Disease Relevance 0.57 Pain Relevance 0.49
Although variations in expression of Sema3a mRNA have been revealed in neurons in both the central and peripheral nervous systems in this context, relatively little is known about NP-1 expression patterns.
Regulation (variations) of Gene_expression (expression) of Sema3a in peripheral nervous systems
2) Confidence 0.12 Published 2000 Journal J. Comp. Neurol. Section Abstract Doc Link 10870088 Disease Relevance 0.27 Pain Relevance 0.11

General Comments

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