INT89100

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Context Info
Confidence 0.65
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 1.76
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CNOT1) cytoplasm (CNOT1)
Anatomy Link Frequency
Plasma 1
liver 1
CNOT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Raphe 1 95.80 Very High Very High Very High
fluoxetine 9 90.40 High High
antagonist 1 75.00 Quite High
sSRI 1 73.00 Quite High
metalloproteinase 11 50.56 Quite High
imagery 35 47.12 Quite Low
Inflammation 5 39.04 Quite Low
COX-2 inhibitor 1 16.64 Low Low
tolerance 2 7.88 Low Low
cytokine 4 6.04 Low Low
Disease Link Frequency Relevance Heat
Contagious Ecthyma 6 99.46 Very High Very High Very High
Cytomegalovirus Infection 12 90.16 High High
Disease 26 89.28 High High
Viral Infection 9 81.16 Quite High
Targeted Disruption 68 80.84 Quite High
Rheumatoid Arthritis 3 72.92 Quite High
Congenital Anomalies 10 59.52 Quite High
Corneal Opacity 13 51.68 Quite High
Adhesions 34 50.00 Quite Low
Alzheimer's Dementia 22 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 1.2 kb IDO PCR fragment was excised with Not I and Bgl II and cloned into the Not I-Bgl II site in the pDOI vector [51], previously modified by the introduction of a Not I site in front of the Eco RI cloning site.
Gene_expression (excised) of Not I
1) Confidence 0.65 Published 2001 Journal BMC Biochem Section Body Doc Link PMC31925 Disease Relevance 0.07 Pain Relevance 0.03
and M13R primers, cloned into pCR4topo vector (Invitrogen), and then a Tol2 NotI fragment was excised and cloned into the NotI site of pCMV-bgal vector (Clontech, Palo Alto, California, United States) in the forward orientation.
Gene_expression (fragment) of NotI
2) Confidence 0.65 Published 2006 Journal PLoS Genetics Section Body Doc Link PMC1635535 Disease Relevance 0.26 Pain Relevance 0
To make pCMV-Tol2, the transposase ORF was amplified from pDB595 using Tol2-NotI-F (5?
Gene_expression (using) of NotI associated with contagious ecthyma
3) Confidence 0.65 Published 2006 Journal PLoS Genetics Section Body Doc Link PMC1635535 Disease Relevance 0.26 Pain Relevance 0
Palmiter, Seattle, WA) [16], which is essential for expression in the liver, was cloned into the NotI/SalI site at the 5?
Gene_expression (site) of NotI in liver
4) Confidence 0.65 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2185514 Disease Relevance 0.42 Pain Relevance 0
An XbaI site and a NotI site were added at the 5?
Gene_expression (site) of NotI
5) Confidence 0.65 Published 2008 Journal Developmental Dynamics Section Body Doc Link PMC2532702 Disease Relevance 0.34 Pain Relevance 0
NotI-RFP-NotI tag was produced by polymerase chain reaction and sub-cloned into G-PS1NotI to generate the GFP-PS1-RFP (G-PS1-R) construct.
Gene_expression (produced) of NotI
6) Confidence 0.58 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2773935 Disease Relevance 0.17 Pain Relevance 0
NotI-RFP-NotI tag was produced by polymerase chain reaction and sub-cloned into G-PS1NotI to generate the GFP-PS1-RFP (G-PS1-R) construct.
Gene_expression (produced) of NotI
7) Confidence 0.58 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2773935 Disease Relevance 0.22 Pain Relevance 0
Plasma levels of oxytocin and adrenal corticotrophic hormone (corticotropin) were measured as peripheral indicators of hypothalamic 5-HT(1A) receptor function.
Gene_expression (levels) of adrenal corticotrophic hormone in Plasma
8) Confidence 0.07 Published 2000 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 10871325 Disease Relevance 0 Pain Relevance 0.56

General Comments

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