INT8911

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Context Info
Confidence 0.05
First Reported 1992
Last Reported 1992
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.91
Pain Relevance 1.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DHCR24) small molecule metabolic process (DHCR24) Golgi apparatus (DHCR24)
endoplasmic reticulum (DHCR24) cytoskeleton (DHCR24) nucleus (DHCR24)
Anatomy Link Frequency
CSF 1
DHCR24 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 24 100.00 Very High Very High Very High
substance P 10 100.00 Very High Very High Very High
Dynorphin 4 100.00 Very High Very High Very High
Pain 2 93.36 High High
Neuropeptide 4 92.32 High High
Enkephalin 2 91.12 High High
Disease Link Frequency Relevance Heat
Arthritis 18 100.00 Very High Very High Very High
Sprains And Strains 4 87.04 High High
Experimental Arthritis 6 85.08 High High
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results demonstrate that both DCE and SPE are affected in the acute phase of arthritis.
Regulation (affected) of DCE associated with arthritis
1) Confidence 0.05 Published 1992 Journal Brain Res. Section Abstract Doc Link 1382800 Disease Relevance 1.11 Pain Relevance 0.96
We investigated the effects of collagen II-induced arthritis on two cerebrospinal fluid (CSF) enzymes converting dynorphin A and substance P (SP), namely dynorphin-converting enzyme (DCE) and substance P endopeptidase (SPE).
Spec (investigated) Regulation (effects) of DCE in CSF associated with dynorphin, substance p and arthritis
2) Confidence 0.04 Published 1992 Journal Brain Res. Section Abstract Doc Link 1382800 Disease Relevance 0.80 Pain Relevance 0.75

General Comments

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