INT89128

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Context Info
Confidence 0.32
First Reported 2000
Last Reported 2009
Negated 2
Speculated 0
Reported most in Body
Documents 7
Total Number 9
Disease Relevance 2.24
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (DSPP) proteinaceous extracellular matrix (DSPP)
Anatomy Link Frequency
dentin 5
teeth 2
cleavage 1
central nervous system 1
DSPP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 43 98.80 Very High Very High Very High
Enkephalin 7 98.68 Very High Very High Very High
Central nervous system 1 97.24 Very High Very High Very High
Inflammatory response 6 92.56 High High
pulpitis 2 81.96 Quite High
Pain 5 37.36 Quite Low
Regional anesthesia 3 5.28 Low Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dentin Dysplasia 14 99.52 Very High Very High Very High
INFLAMMATION 49 98.80 Very High Very High Very High
Necrosis 6 98.16 Very High Very High Very High
Pulpitis 2 81.96 Quite High
Dentinogenesis Imperfecta 86 54.72 Quite High
Cleidocranial Dysplasia 59 54.00 Quite High
Infection 8 51.12 Quite High
Disease 13 49.84 Quite Low
Pain 5 37.36 Quite Low
Hemorrhage 15 29.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following cleavage, DPP rapidly moves to the mineralisation front where it associates with type I collagen [30].
DPP Binding (cleavage) of in cleavage
1) Confidence 0.32 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2600777 Disease Relevance 0.11 Pain Relevance 0
Dentin dysplasia is a genetic defect of dentin formation inherited as an autosomal dominant trait.
dentin Binding (formation) of in Dentin associated with dentin dysplasia
2) Confidence 0.23 Published 2009 Journal Quintessence Int Section Abstract Doc Link 19417880 Disease Relevance 0.38 Pain Relevance 0
It is characterized by normal enamel but atypical dentin formation with abnormal pulpal morphology.
dentin Binding (formation) of in dentin
3) Confidence 0.22 Published 2009 Journal Quintessence Int Section Abstract Doc Link 19417880 Disease Relevance 0.40 Pain Relevance 0
We have found activity of dipeptidyl peptidase (DPP) III, one of the most important enkephalin-degrading enzymes in the central nervous system, in human neutrophils.
DPP Binding (activity) of in central nervous system associated with central nervous system and enkephalin
4) Confidence 0.20 Published 2000 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 10873616 Disease Relevance 0 Pain Relevance 0.38
After 1 day, no dentin bridge formation was observed in any of the 5 teeth in this group.
dentin Neg (no) Binding (formation) of in dentin
5) Confidence 0.01 Published 2009 Journal The Open Dentistry Journal Section Body Doc Link PMC2681172 Disease Relevance 0.26 Pain Relevance 0.13
No dentin bridge formation was observed in any of the 5 teeth in this group after 7 days.
dentin Neg (No) Binding (formation) of in teeth
6) Confidence 0.01 Published 2009 Journal The Open Dentistry Journal Section Body Doc Link PMC2681172 Disease Relevance 0.33 Pain Relevance 0.17
Dentin bridge formation was seen in two teeth with some distance from the material interface (14 and 21 days).
Dentin Binding (formation) of in teeth
7) Confidence 0.01 Published 2009 Journal The Open Dentistry Journal Section Abstract Doc Link PMC2681172 Disease Relevance 0.09 Pain Relevance 0.05
While intrapulpal implantation of TGF-beta1 can induce differentiation of odontoblast-like cells and reparative dentin formation in the immediate vicinity of the implanted site [26], its usefulness as a pulp capping agent is limited [27].
dentin Binding (formation) of in dentin
8) Confidence 0.01 Published 2006 Journal Head Face Med Section Body Doc Link PMC1481630 Disease Relevance 0.26 Pain Relevance 0.13
In vivo ultrasound-mediated delivery of BMP-11 (Growth/differentiation factor 11) cDNA to mechanically-exposed canine pulp tissue was effective at promoting significant amounts of reparative dentin formation in vivo, with minimal pulpal inflammation or necrosis [43].
dentin Binding (formation) of in dentin associated with necrosis and inflammation
9) Confidence 0.01 Published 2006 Journal Head Face Med Section Body Doc Link PMC1481630 Disease Relevance 0.41 Pain Relevance 0.13

General Comments

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