INT89235

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Context Info
Confidence 0.61
First Reported 2000
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.80
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Abcc1) transmembrane transport (Abcc1) cytoplasm (Abcc1)
oxidoreductase activity (Abcc1) nucleolus (Abcc1) nucleus (Abcc1)
Abcc1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 1 96.28 Very High Very High Very High
addiction 1 94.24 High High
Dopamine 4 92.80 High High
Bile 10 18.68 Low Low
anesthesia 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Taxol 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 16 89.44 High High
Cancer 39 83.64 Quite High
Osteogenic Sarcomas 1 80.28 Quite High
Plasmacytoma 2 79.60 Quite High
Metastasis 4 66.64 Quite High
Shock 10 50.00 Quite Low
Disease 1 33.92 Quite Low
Fever 7 17.92 Low Low
Hodgkin's Disease 1 10.64 Low Low
Stress 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, over-expression of MRP1 did not affect transport of the acid metabolites.
Neg (not) Regulation (affect) of Gene_expression (over) of MRP1
1) Confidence 0.61 Published 2000 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 10882041 Disease Relevance 0 Pain Relevance 0.30
Some members of the Oatp and Mrp transporter families are known to transport conjugates of steroid hormones such as DHEAS and 17?
Regulation (members) of Gene_expression (families) of Mrp transporter
2) Confidence 0.42 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2944077 Disease Relevance 0 Pain Relevance 0
Despite high concentrations of the cytostatic drug and the exposition towards hyperthermic temperatures, only temporary effects on gene expression, that is, mrp1 (suppression) and mrp2 (induction) could be observed.
Regulation (effects) of Gene_expression (expression) of mrp1
3) Confidence 0.15 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2903950 Disease Relevance 0.80 Pain Relevance 0

General Comments

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