INT89286

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Context Info
Confidence 0.69
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Drd3) signal transducer activity (Drd3)
Drd3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 1 88.56 High High
Substantia nigra 2 85.60 High High
substance P 1 77.16 Quite High
Dynorphin 1 76.68 Quite High
Dopamine 1 62.36 Quite High
Enkephalin 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Behavioural sensitization, induction of D3 receptor binding and changes in prodynorphin/preprotachykinin ratio were all prevented together when levodopa was continuously delivered or intermittently delivered in combination with R-(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4, 5-tetrahydro-1H-3-benzazepine (SCH 23390), a selective D1 receptor antagonist.
Positive_regulation (induction) of D3 receptor Binding (binding) of associated with antagonist
1) Confidence 0.69 Published 2000 Journal Eur. J. Neurosci. Section Abstract Doc Link 10886351 Disease Relevance 0 Pain Relevance 0.23

General Comments

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