INT89363

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Context Info
Confidence 0.11
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.11
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ahsg) extracellular region (Ahsg) protein complex assembly (Ahsg)
protein complex (Ahsg)
Anatomy Link Frequency
dorsal horn 1
Ahsg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 3 99.52 Very High Very High Very High
nMDA receptor 1 99.12 Very High Very High Very High
Arthritis 6 98.96 Very High Very High Very High
spinal dorsal horn 1 90.72 High High
Inflammatory response 1 84.48 Quite High
cINOD 3 75.00 Quite High
intrathecal 1 74.16 Quite High
Inflammation 3 71.84 Quite High
referred pain 1 26.80 Quite Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 2 100.00 Very High Very High Very High
Experimental Arthritis 5 98.96 Very High Very High Very High
Stress Incontinence 3 87.44 High High
INFLAMMATION 6 84.48 Quite High
Arthritis 1 66.64 Quite High
Pressure And Volume Under Development 1 28.24 Quite Low
Referred Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of adjuvant arthritis (AA) on the pattern of rat serum proteins includes the upregulation of haptoglobin, orosomucoid, alpha2-macroglobulin, serine protease inhibitor-3, thiostatin, alpha1-antitrypsin, C-reactive protein, and the downregulation of kallikrein-binding protein, alpha1-inhibitor III, apolipoprotein A-I, alpha2-HS-glycoprotein, albumin, apolipoprotein A-IV, transthyretin and transferrin.
Positive_regulation (upregulation) of alpha2-HS-glycoprotein associated with experimental arthritis, disorder of lipid metabolism and arthritis
1) Confidence 0.11 Published 2000 Journal Electrophoresis Section Abstract Doc Link 10892728 Disease Relevance 0.86 Pain Relevance 0.37
When compared with vehicle solution, intracolonic mustard oil sensitized the NMDA receptor NR2B subunit-dependent reflex activity and increased expression levels of phosphorylated Akt (pAkt) and phosphorylated NR2B (pNR2B) in dorsal horn.
Positive_regulation (increased) of phosphorylated NR2B in dorsal horn associated with nmda receptor and dorsal horn
2) Confidence 0.03 Published 2010 Journal J. Neurochem. Section Abstract Doc Link 20067569 Disease Relevance 0.25 Pain Relevance 0.26

General Comments

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