INT89425

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Context Info
Confidence 0.59
First Reported 2000
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.38
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (HLA-DRB3) signal transduction (HLA-DRB3) Golgi apparatus (HLA-DRB3)
endoplasmic reticulum (HLA-DRB3) plasma membrane (HLA-DRB3)
HLA-DRB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
reflex sympathetic dystrophy 4 99.88 Very High Very High Very High
imagery 2 69.24 Quite High
Pain 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Complex Regional Pain Syndromes 4 99.88 Very High Very High Very High
Dystonia 4 99.18 Very High Very High Very High
Disease 7 98.84 Very High Very High Very High
Movement Disorders 3 98.30 Very High Very High Very High
Parkinsonian Disorders 2 97.52 Very High Very High Very High
Autonomic Nervous System Disease 5 97.24 Very High Very High Very High
Chorea 1 96.52 Very High Very High Very High
Multiple System Atrophy 3 93.92 High High
Ataxia 1 92.20 High High
Overactive Bladder 1 88.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared with controls, a significant elevation of HLA-DR13 was found in the patients.
Positive_regulation (elevation) of HLA-DR13
1) Confidence 0.59 Published 2000 Journal Ann. Neurol. Section Abstract Doc Link 10894225 Disease Relevance 0.51 Pain Relevance 0.25
Dysautonomia has also been recognised in other movement disorders, examples being the combination of dystonia and complex regional pain syndrome with elevated HLA-DR13 and late onset Huntington's disease presenting with dominant parkinsonism and minimal chorea.
Positive_regulation (elevated) of HLA-DR13 associated with chorea, complex regional pain syndromes, movement disorders, disease, autonomic nervous system disease, reflex sympathetic dystrophy, dystonia and parkinsonian disorders
2) Confidence 0.52 Published 2001 Journal Curr. Opin. Neurol. Section Abstract Doc Link 11470968 Disease Relevance 1.88 Pain Relevance 0.17

General Comments

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