INT89428

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Context Info
Confidence 0.36
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.93
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TG) extracellular space (TG) extracellular region (TG)
Golgi apparatus (TG) endoplasmic reticulum (TG)
Anatomy Link Frequency
thyroid 2
TG (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 40 95.80 Very High Very High Very High
tolerance 2 94.72 High High
headache 5 93.36 High High
cva 1 85.08 High High
Pain 8 71.20 Quite High
Angina 1 70.40 Quite High
imagery 49 69.76 Quite High
depression 4 67.84 Quite High
palliative 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 95 99.84 Very High Very High Very High
Thyroid Neoplasm 255 99.52 Very High Very High Very High
Metastasis 85 98.98 Very High Very High Very High
Toxicity 6 94.72 High High
Disease 123 94.44 High High
Vomiting 1 93.80 High High
Headache 5 93.36 High High
Liver Failure 1 87.76 High High
Hemorrhage 1 85.08 High High
Necrosis 2 84.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemical studies of 2 tumors showed positivity for thyroid transcription factor-1, keratin, and carcinoembryonic antigen and negativity for thyroglobulin.
Regulation (positivity) of thyroglobulin in thyroid associated with cancer
1) Confidence 0.36 Published 2004 Journal Am. J. Clin. Pathol. Section Abstract Doc Link 15272538 Disease Relevance 0.95 Pain Relevance 0.11
Moreover, regular serial Tg-on measurement with a sensitive Tg assay anyhow would have identified this solely patient, since the change in Tg over time is more informative than a single Tg determination [27].
Regulation (regular) of Tg-on
2) Confidence 0.31 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1950687 Disease Relevance 0.64 Pain Relevance 0.03
Thyroglobulin values above 10 ng x ml(-1) were found in seven patients, of whom four had similar findings when scanned after withdrawal of thyroid hormone.
Regulation (values) of Thyroglobulin in thyroid associated with withdrawal
3) Confidence 0.27 Published 2000 Journal Nucl Med Commun Section Abstract Doc Link 10894560 Disease Relevance 0.33 Pain Relevance 0.19
The primary endpoint was the: (1) the qualitative effect of 13-CRA RDT on 131-I uptake in confirmed non-functional NMTC metastases (scintigraphic response) and (2) the quantitative effect of 13-CRA RD Ton thyroglobulin serum level during therapy course.
Regulation (effect) of thyroglobulin associated with metastasis
4) Confidence 0.26 Published 2009 Journal Thyroid Res Section Body Doc Link PMC2739165 Disease Relevance 1.06 Pain Relevance 0.31
Thyroglobulin response
Regulation (response) of Thyroglobulin
5) Confidence 0.26 Published 2009 Journal Thyroid Res Section Body Doc Link PMC2739165 Disease Relevance 0.18 Pain Relevance 0.08
Seventeen (95%) of 19 patients for whom serial thyroglobulin levels were available showed a marked and rapid response in thyroglobulin levels with a mean decrease of 70%.
Regulation (response) of thyroglobulin
6) Confidence 0.19 Published 2010 Journal Journal of Thyroid Research Section Body Doc Link PMC2956973 Disease Relevance 0.78 Pain Relevance 0

General Comments

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