INT89501

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Context Info
Confidence 0.01
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Ptgs2) aging (Il6) endoplasmic reticulum (Ptgs2)
enzyme binding (Ptgs2) protein complex (Ptgs2) cytoplasm (Ptgs2)
Il6 (Rattus norvegicus)
Ptgs2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 3 94.16 High High
agonist 2 89.20 High High
substance P 1 86.72 High High
Inflammation 1 77.60 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Ulcers 4 100.00 Very High Very High Very High
Necrosis 1 98.22 Very High Very High Very High
Cancer 1 98.04 Very High Very High Very High
Peptic Ulcer 4 90.88 High High
Diarrhoea 2 75.00 Quite High
Insect Bites And Stings 1 68.88 Quite High
Gastritis 1 67.16 Quite High
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of proinflammatory genes tumor necrosis factor-alpha, inducible nitric oxide synthase (iNOS), interleukin (IL)-1beta, IL-6, and cyclooxygenase-2 was upregulated by ulcer induction but reduced by sangre de grado treatment, particularly iNOS and IL-6.
IL-6 Positive_regulation (upregulated) of cyclooxygenase-2 associated with necrosis, cancer and ulcers
1) Confidence 0.01 Published 2000 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 10898763 Disease Relevance 1.07 Pain Relevance 0.35

General Comments

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