INT89515

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Context Info
Confidence 0.09
First Reported 2000
Last Reported 2000
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Fosl1) extracellular region (Pnoc) nucleus (Fosl1)
DNA binding (Fosl1)
Anatomy Link Frequency
sciatic nerve 2
Pnoc (Rattus norvegicus)
Fosl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
orphanin 4 100.00 Very High Very High Very High
Thermal hyperalgesia 3 100.00 Very High Very High Very High
agonist 2 100.00 Very High Very High Very High
spinal dorsal horn 1 99.32 Very High Very High Very High
Eae 4 97.96 Very High Very High Very High
opioid receptor 1 95.16 Very High Very High Very High
Sciatic nerve 5 94.80 High High
Spinal cord 1 94.48 High High
analgesia 1 89.92 High High
withdrawal 1 57.44 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 4 100.00 Very High Very High Very High
Neuropathic Pain 2 97.96 Very High Very High Very High
Injury 3 95.96 Very High Very High Very High
Nervous System Injury 6 94.48 High High
Nociception 2 93.48 High High
Diabetic Nephropathy 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We investigated the effect of nociceptin, an ORL1 receptor agonist, on the development of thermal hyperalgesia and the expression of Fos-like immunoreactivity (Fos-LI) in the spinal dorsal horn induced by two neuropathic pain models, the chronic constriction injury model and the partial sciatic nerve injury model.
nociceptin Spec (investigated) Regulation (effect) of Gene_expression (expression) of Fos-like immunoreactivity in sciatic nerve associated with nervous system injury, eae, spinal dorsal horn, thermal hyperalgesia, orphanin, injury, agonist and sciatic nerve
1) Confidence 0.09 Published 2000 Journal Brain Res. Section Abstract Doc Link 10899286 Disease Relevance 0.98 Pain Relevance 0.93

General Comments

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