INT89544

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Context Info
Confidence 0.79
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.05
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NEFL)
Anatomy Link Frequency
cortex 1
NEFL (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 11 98.04 Very High Very High Very High
methadone 1 89.12 High High
opiate 1 87.92 High High
addiction 2 82.36 Quite High
Inflammation 8 37.00 Quite Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Abeta 1 5.00 Very Low Very Low Very Low
intrathecal 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lyme Neuroborreliosis 53 99.92 Very High Very High Very High
Paralysis 17 98.72 Very High Very High Very High
Overdose 1 88.28 High High
Amyloid Plaque 2 86.00 High High
Opiate Addiction 2 82.36 Quite High
Congenital Anomalies 1 81.56 Quite High
Acute Disease 2 59.84 Quite High
Alzheimer's Dementia 23 50.00 Quite Low
INFLAMMATION 8 37.00 Quite Low
Neurologic Manifestations 1 29.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Total-tau, Phospho-tau and NFL
Phosphorylation (tau) of NFL
1) Confidence 0.79 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2902447 Disease Relevance 0.80 Pain Relevance 0
Decreased levels of nonphosphorylated NF-H (42-32%), NF-M (14-9%) and NF-L (30-29%) were found in the prefrontal cortex of opioid addicts compared with sex, age, and postmortem delay-matched controls.
Phosphorylation (nonphosphorylated) of NF-L in cortex associated with opioid
2) Confidence 0.68 Published 2000 Journal J. Neurosci. Res. Section Abstract Doc Link 10900081 Disease Relevance 0.25 Pain Relevance 0.86

General Comments

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