INT89549

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Context Info
Confidence 0.43
First Reported 2000
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.42
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (NEFH) cell death (NEFH) molecular_function (NEFH)
Anatomy Link Frequency
brains 1
optic nerves 1
NEFH (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 11 97.56 Very High Very High Very High
methadone 1 81.36 Quite High
opiate 1 80.16 Quite High
addiction 2 74.60 Quite High
anesthesia 10 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
ketamine 8 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glaucoma 182 98.88 Very High Very High Very High
Frailty 4 88.76 High High
Syndrome 4 87.76 High High
Sprains And Strains 4 85.80 High High
Overdose 1 80.52 Quite High
Opiate Addiction 2 74.60 Quite High
Congenital Anomalies 1 73.80 Quite High
Ganglion Cysts 46 72.64 Quite High
Familial Adenomatous Polyposis 8 41.16 Quite Low
Ocular Hypertension 36 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, increased levels of phosphorylated NF-H (58-41%) and NF-M (56-28%) were found in the same brains of opioid addicts.
Positive_regulation (increased) of NF-H in brains associated with opioid
1) Confidence 0.43 Published 2000 Journal J. Neurosci. Res. Section Abstract Doc Link 10900081 Disease Relevance 0.23 Pain Relevance 0.86
The higher NEFH increase in sample 529 may be due to retinal contamination or to higher IOP exposure in that spontaneous glaucoma compared to the laser treated samples.


Positive_regulation (increase) of NEFH associated with glaucoma
2) Confidence 0.25 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2567987 Disease Relevance 0.60 Pain Relevance 0
Two NEFH antibodies were used to examine the localization of upregulated NEFH in the axons of optic nerves of healthy and experimental glaucoma monkeys.
Spec (examine) Positive_regulation (upregulated) of NEFH in optic nerves associated with glaucoma
3) Confidence 0.25 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2567987 Disease Relevance 0.59 Pain Relevance 0

General Comments

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