INT89599

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.23
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.41
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (TBXAS1) small molecule metabolic process (TBXAS1) endoplasmic reticulum (TBXAS1)
Anatomy Link Frequency
monocytes 1
thrombocyte 1
TBXAS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory stimuli 1 97.76 Very High Very High Very High
cINOD 57 97.74 Very High Very High Very High
cytokine 5 92.08 High High
diclofenac 3 91.12 High High
Inflammation 23 68.48 Quite High
COX-2 inhibitor 13 66.88 Quite High
Pain 8 53.84 Quite High
Osteoarthritis 2 47.44 Quite Low
rheumatoid arthritis 1 46.68 Quite Low
Spinal cord 1 32.24 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 30 97.76 Very High Very High Very High
Pain 8 53.84 Quite High
Osteoarthritis 2 47.44 Quite Low
Rheumatoid Arthritis 1 46.68 Quite Low
Necrosis 1 35.24 Quite Low
Cancer 4 34.88 Quite Low
Ulcers 11 5.00 Very Low Very Low Very Low
Hemorrhage 7 5.00 Very Low Very Low Very Low
Fever 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This has led to speculation regarding possible linkage of COX isozymes with PGE and TXA synthase.
TXA synthase Binding (linkage) of
1) Confidence 0.23 Published 2000 Journal J. Immunol. Section Abstract Doc Link 10903770 Disease Relevance 0.05 Pain Relevance 0.14
It is proposed that different kinetics of PGE synthase and TXA synthase account for the patterns of production of these eicosanoids in monocytes under a variety of experimental conditions.
TXA synthase Binding (account) of in monocytes
2) Confidence 0.23 Published 2000 Journal J. Immunol. Section Abstract Doc Link 10903770 Disease Relevance 0.09 Pain Relevance 0.18
Studies with this new assay have finally shown that none of the NSAIDs used previously selectively inhibited COX-2, in other words under therapeutic conditions it allowed thrombocyte aggregation and thromboxane synthase to be kept intact while the formation of PGE2 after an inflammatory stimulus was suppressed.
thromboxane synthase Binding (aggregation) of in thrombocyte associated with cinod and inflammatory stimuli
3) Confidence 0.02 Published 2000 Journal Arthritis Res Section Body Doc Link PMC130140 Disease Relevance 0.27 Pain Relevance 0.50

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox