INT89615

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Context Info
Confidence 0.79
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.50
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (FABP3) cytoskeletal protein binding (FABP3) cytosol (FABP3)
Anatomy Link Frequency
myocardium 1
heart 1
kidney 1
FABP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 43 87.84 High High
Inflammation 29 66.44 Quite High
cva 15 65.00 Quite High
ischemia 35 44.72 Quite Low
Inflammatory marker 4 14.16 Low Low
cytokine 7 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 110 98.92 Very High Very High Very High
Injury 23 98.28 Very High Very High Very High
Disease 16 93.52 High High
Renal Failure 6 92.36 High High
Acute Coronary Syndrome 76 92.12 High High
Angina 46 87.84 High High
Infarction 6 81.32 Quite High
Death 25 67.00 Quite High
INFLAMMATION 35 66.44 Quite High
Cv Unclassified Under Development 23 65.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When the myocardium is injured, as in the case of myocardial infarction, low molecular weight cytoplasmic proteins including H-FABP are released into the circulation and H-FABP is detectable in a blood sample.
Localization (released) of H-FABP in myocardium associated with myocardial infarction
1) Confidence 0.79 Published 2000 Journal Clin. Chem. Lab. Med. Section Abstract Doc Link 10905760 Disease Relevance 0.38 Pain Relevance 0
Comparison of usefulness of heart-type fatty acid binding protein versus cardiac troponin T for diagnosis of acute myocardial infarction.
Localization (usefulness) of heart-type fatty acid binding protein in heart associated with myocardial infarction
2) Confidence 0.66 Published 2010 Journal Am. J. Cardiol. Section Title Doc Link 20102882 Disease Relevance 0.63 Pain Relevance 0.17
H-FABP is rapidly released into the circulation following myocardial injury, and is detectable within 2 to 3 hours of the onset of clinical symptoms [48].
Localization (released) of H-FABP associated with injury
3) Confidence 0.39 Published 2008 Journal Crit Care Section Body Doc Link PMC2481437 Disease Relevance 1.17 Pain Relevance 0.16
The rapid release of H-FABP can also be used for the detection of successful coronary reperfusion in patients with AMI (Suzuki M et al. 2005).
Localization (release) of H-FABP associated with myocardial infarction
4) Confidence 0.12 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.64 Pain Relevance 0
The combination of initial hFABP release after symptom onset, rapid kidney clearance from the circulation and high cardiac specificity suggests great potential for clinical use.
Localization (release) of hFABP in kidney
5) Confidence 0.01 Published 2007 Journal Cardiology Section Abstract Doc Link 16960442 Disease Relevance 0.69 Pain Relevance 0.09

General Comments

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