INT89689

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Context Info
Confidence 0.37
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.55
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

chromosome segregation (Brca1) intracellular (Brca1) enzyme binding (Brca1)
DNA binding (Brca1) protein complex (Brca1) ligase activity (Brca1)
Anatomy Link Frequency
mammary gland 1
epithelial cells 1
Brca1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 12 99.52 Very High Very High Very High
Dismenorea 1 67.44 Quite High
fibrosis 1 66.76 Quite High
palliative 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 182 96.60 Very High Very High Very High
Breast Cancer 247 95.00 High High
Targeted Disruption 12 92.80 High High
Ovarian Cancer 7 92.56 High High
Genomic Instability 4 90.48 High High
Male Breast Neoplasms 2 84.40 Quite High
Reprotox - General 1 2 77.92 Quite High
Pancreatic Cancer 2 76.56 Quite High
Disease 32 76.40 Quite High
Lymphatic System Cancer 4 73.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mice heterozygous for a Brca1 or Brca2 mutation display distinct mammary gland and ovarian phenotypes in response to diethylstilbestrol.
Brca1 Binding (mutation) of in mammary gland associated with inflammation
1) Confidence 0.37 Published 2000 Journal Cancer Res. Section Title Doc Link 10910057 Disease Relevance 0.70 Pain Relevance 0.18
Perhaps the most interesting among BRCA1 protein-protein interactions in mammary epithelial cells is the one with the ER?.
BRCA1 Binding (interactions) of in epithelial cells
2) Confidence 0.30 Published 2010 Journal Clinical Medicine Insights. Oncology Section Body Doc Link PMC2883240 Disease Relevance 0.68 Pain Relevance 0
Its gene shares homology with BRCA1, and its encoded protein has similar biochemical functions to BRCA1.
BRCA1 Binding (homology) of
3) Confidence 0.23 Published 2010 Journal Clinical Medicine Insights. Oncology Section Body Doc Link PMC2883240 Disease Relevance 1.17 Pain Relevance 0

General Comments

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