INT89764

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Context Info
Confidence 0.42
First Reported 2000
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.22
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR4A1) signal transduction (NR4A1) nucleus (NR4A1)
DNA binding (NR4A1)
NR4A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 82.92 Quite High
alcohol 1 49.80 Quite Low
Central nervous system 1 40.88 Quite Low
fibrosis 1 12.80 Low Low
cytokine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
calcitonin gene related peptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 24 97.40 Very High Very High Very High
Colon Cancer 5 95.40 Very High Very High Very High
Apoptosis 14 93.96 High High
Rheumatoid Arthritis 24 91.84 High High
INFLAMMATION 1 82.36 Quite High
Uterine Fibroids 72 76.28 Quite High
Death 1 21.80 Low Low
Cirrhosis 1 12.80 Low Low
Disease 5 5.00 Very Low Very Low Very Low
Neuroblastoma 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The transcript- and protein-level, the transcriptional activity of Nur77 promoter, and the DNA binding of Nur77 were significantly induced following indomethacin treatment.
Nur77 Binding (binding) of
1) Confidence 0.42 Published 2000 Journal Biol. Pharm. Bull. Section Abstract Doc Link 10919358 Disease Relevance 0.90 Pain Relevance 0.17
NR4A1 was originally recognized for its role in cell proliferation and differentiation.
NR4A1 Binding (recognized) of
2) Confidence 0.22 Published 2007 Journal BMC Womens Health Section Body Doc Link PMC1852551 Disease Relevance 1.32 Pain Relevance 0

General Comments

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