INT89766

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Context Info
Confidence 0.17
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.15

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endoplasmic reticulum (SRF) nucleolus (SRF) nucleus (SRF)
transcription factor binding (SRF) cytoplasm (SRF)
SRF (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 75.80 Quite High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 1 88.64 High High
Colon Cancer 4 88.28 High High
Apoptosis 5 86.84 High High
Cancer 2 77.16 Quite High
INFLAMMATION 1 75.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among the two potential trans-acting factors that activate Nur77-promoter, indomethacin induced DNA binding and reporter gene activity of AP-1, but not that of related serum response factor (RSRF), suggesting that the transcriptional induction of Nur77 may be mediated through activation of AP-I.
related serum response factor Binding (binding) of
1) Confidence 0.17 Published 2000 Journal Biol. Pharm. Bull. Section Abstract Doc Link 10919358 Disease Relevance 0.89 Pain Relevance 0.15

General Comments

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