INT89772

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Context Info
Confidence 0.21
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.29
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (APEX1) mitochondrion (APEX1) lyase activity (APEX1)
ribosome (APEX1) endoplasmic reticulum (APEX1) intracellular (APEX1)
Anatomy Link Frequency
pituitary 1
APEX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 11 98.96 Very High Very High Very High
cINOD 2 68.72 Quite High
Calcium channel 2 25.48 Quite Low
anesthesia 1 23.92 Low Low
Angina 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acromegaly 8 99.44 Very High Very High Very High
Myasthenia Gravis 27 98.90 Very High Very High Very High
Disease 49 98.48 Very High Very High Very High
Rheumatoid Arthritis 2 97.12 Very High Very High Very High
Apoptosis 5 93.04 High High
Malignant Neoplastic Disease 2 86.40 High High
Hypersensitivity 2 85.80 High High
Colon Cancer 4 81.20 Quite High
Cv Unclassified Under Development 2 76.28 Quite High
Sudden Infant Death Syndrome 2 73.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By applying ApEn to measurements of growth hormone (GH) every 5 min for 24 hours in healthy control individuals and patients with acromegaly, reduced orderliness (i.e. increased ApEn) was observed in acromegaly [125]; and normalization of GH ApEn values was demonstrated after pituitary surgery for acromegaly [126].
Positive_regulation (increased) of ApEn in pituitary associated with acromegaly
1) Confidence 0.21 Published 2004 Journal Crit Care Section Body Doc Link PMC1065053 Disease Relevance 0.63 Pain Relevance 0
This is performed by evaluating data sequences of length m, and determining the likelihood that other runs in the data set of the same length m are similar (within a specified tolerance r); thus two parameters, m and r, must be fixed to calculate ApEn.
Positive_regulation (calculate) of ApEn associated with tolerance
2) Confidence 0.15 Published 2004 Journal Crit Care Section Body Doc Link PMC1065053 Disease Relevance 0 Pain Relevance 0.05
Among the two potential trans-acting factors that activate Nur77-promoter, indomethacin induced DNA binding and reporter gene activity of AP-1, but not that of related serum response factor (RSRF), suggesting that the transcriptional induction of Nur77 may be mediated through activation of AP-I.
Positive_regulation (activation) of AP-I
3) Confidence 0.13 Published 2000 Journal Biol. Pharm. Bull. Section Abstract Doc Link 10919358 Disease Relevance 0.86 Pain Relevance 0.14
The best understood example of an antibody-mediated disease is myasthenia gravis with acetylcholine receptor antibodies (for a review, see Ref. 9).
Positive_regulation (see) of Ref associated with myasthenia gravis and disease
4) Confidence 0.05 Published 2009 Journal Molecular & Cellular Proteomics : MCP Section Body Doc Link PMC2716719 Disease Relevance 0.80 Pain Relevance 0

General Comments

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