INT89806

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Context Info
Confidence 0.29
First Reported 2000
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.07
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prkaca) nucleoplasm (Prkaca) mitochondrion (Prkaca)
Golgi apparatus (Prkaca) plasma membrane (Prkaca) nucleus (Prkaca)
Prkaca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
adenocard 1 99.32 Very High Very High Very High
agonist 2 86.28 High High
Enkephalin 2 25.00 Low Low
fibrosis 2 5.00 Very Low Very Low Very Low
5HT 1 5.00 Very Low Very Low Very Low
Piles 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 1 75.00 Quite High
Constipation 39 50.00 Quite Low
Body Weight 4 44.80 Quite Low
Diarrhoea 3 5.00 Very Low Very Low Very Low
Spasticity 2 5.00 Very Low Very Low Very Low
Cystic Fibrosis 2 5.00 Very Low Very Low Very Low
Cardiovascular Disease 1 5.00 Very Low Very Low Very Low
Anorectal Disorders 1 5.00 Very Low Very Low Very Low
Vomiting 1 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BACKGROUND: Previous in vivo studies show that acute ethanol exposure sequentially increases protein kinase A (PKA) activity, the phosphorylation of the adenosine 3':5'-cyclic monophosphate (cAMP)-dependent transcription factor, CREB, and finally proenkephalin gene expression.
Transcription (activity) of PKA associated with adenocard
1) Confidence 0.29 Published 2000 Journal Alcohol. Clin. Exp. Res. Section Abstract Doc Link 10923996 Disease Relevance 0.07 Pain Relevance 0.05
Measurement of intracellular cAMP and Protein Kinase A (PKA) activity
Transcription (activity) of PKA
2) Confidence 0.08 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2553183 Disease Relevance 0 Pain Relevance 0.04

General Comments

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