INT89812

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Context Info
Confidence 0.24
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a) extracellular space (Il1a) extracellular region (Il1a)
Il1a (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 8 100.00 Very High Very High Very High
cytokine 2 94.40 High High
Disease Link Frequency Relevance Heat
Hepatotoxicity 4 100.00 Very High Very High Very High
Sprains And Strains 2 100.00 Very High Very High Very High
Injury 1 52.76 Quite High
Toxicity 2 46.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-1 alpha pretreatment equally protected against the hepatotoxicity of acetaminophen and CCl(4) in both strains, and suppressed the total microsomal P450 and P450 enzyme-catalyzed testosterone hydroxylation to a similar extent.
Negative_regulation (suppressed) of Gene_expression (pretreatment) of IL-1 alpha associated with paracetamol, hepatotoxicity and sprains and strains
1) Confidence 0.24 Published 2000 Journal Toxicology Section Abstract Doc Link 10924799 Disease Relevance 0.58 Pain Relevance 0.66

General Comments

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