INT89813

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Context Info
Confidence 0.28
First Reported 2000
Last Reported 2000
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a) extracellular space (Il1a) extracellular region (Il1a)
Il1a (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 100.00 Very High Very High Very High
Paracetamol 8 96.76 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hepatotoxicity 4 94.24 High High
Sprains And Strains 2 84.96 Quite High
Injury 1 33.24 Quite Low
Toxicity 2 26.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This protective effect of LPS appears to be mediated through the release of cytokines such as IL-1 alpha, which in turn suppresses the cytochrome P450 responsible for the activation of acetaminophen and CCl(4) to reactive metabolites.
Spec (appears) Positive_regulation (mediated) of Localization (release) of IL-1 alpha associated with paracetamol and cytokine
1) Confidence 0.28 Published 2000 Journal Toxicology Section Abstract Doc Link 10924799 Disease Relevance 0.47 Pain Relevance 0.55

General Comments

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