INT89828

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Context Info
Confidence 0.10
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.54
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Grip2) plasma membrane (Grip2) cytoskeleton (Grip2)
cellular_component (Atp4b) cytoplasm (Grip2)
Anatomy Link Frequency
frontal cortex 3
hippocampus 1
Atp4b (Rattus norvegicus)
Grip2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
noradrenaline 24 99.84 Very High Very High Very High
Hippocampus 4 99.00 Very High Very High Very High
tetrodotoxin 2 80.68 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 10 98.36 Very High Very High Very High
Cognitive Disorder 4 96.76 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that the capacity of S18986-1 to enhance AMPA receptor-mediated release of noradrenaline in rat hippocampus and frontal cortex, could contribute to the cognition enhancing mechanisms of S18986-1.
S18986-1 Positive_regulation (enhance) of Localization (release) of AMPA in frontal cortex associated with cognitive disorder, noradrenaline, urological neuroanatomy and hippocampus
1) Confidence 0.10 Published 2000 Journal Eur. J. Pharmacol. Section Abstract Doc Link 10924919 Disease Relevance 0.27 Pain Relevance 0.49
These results suggest that the capacity of S18986-1 to enhance AMPA receptor-mediated release of noradrenaline in rat hippocampus and frontal cortex, could contribute to the cognition enhancing mechanisms of S18986-1.
S18986-1 Positive_regulation (enhance) of in hippocampus Localization (release) of AMPA in frontal cortex associated with cognitive disorder, noradrenaline, urological neuroanatomy and hippocampus
2) Confidence 0.03 Published 2000 Journal Eur. J. Pharmacol. Section Abstract Doc Link 10924919 Disease Relevance 0.27 Pain Relevance 0.49

General Comments

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