INT89873

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Context Info
Confidence 0.23
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.29

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nucleus (Gata4) plasma membrane (Pdyn) DNA binding (Gata4)
transcription factor binding (Gata4) cell-cell signaling (Gata4)
Pdyn (Mus musculus)
Gata4 (Mus musculus)
Pain Link Frequency Relevance Heat
Dynorphin 10 100.00 Very High Very High Very High
Opioid 10 85.28 High High
opioid receptor 2 76.80 Quite High
Enkephalin 6 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the absence of DMSO, dynorphin B triggered GATA-4 and Nkx-2.5 gene expression and led to the appearance of both alpha-myosin heavy chain and myosin light chain-2V transcripts, two markers of cardiac differentiation.
dynorphin B Positive_regulation (triggered) of Gene_expression (expression) of GATA-4 associated with dynorphin
1) Confidence 0.23 Published 2000 Journal Circ. Res. Section Abstract Doc Link 10926868 Disease Relevance 0 Pain Relevance 0.64
In the absence of DMSO, dynorphin B triggered GATA-4 and Nkx-2.5 gene expression and led to the appearance of both alpha-myosin heavy chain and myosin light chain-2V transcripts, two markers of cardiac differentiation.
dynorphin B Positive_regulation (led) of Gene_expression (expression) of GATA-4 associated with dynorphin
2) Confidence 0.23 Published 2000 Journal Circ. Res. Section Abstract Doc Link 10926868 Disease Relevance 0 Pain Relevance 0.64

General Comments

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