INT89878

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Context Info
Confidence 0.35
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.29

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cell differentiation (Nkx2-5) nucleus (Nkx2-5) plasma membrane (Pdyn)
DNA binding (Nkx2-5) transcription factor binding (Nkx2-5) cytoplasm (Nkx2-5)
Pdyn (Mus musculus)
Nkx2-5 (Mus musculus)
Pain Link Frequency Relevance Heat
Dynorphin 10 100.00 Very High Very High Very High
Opioid 10 85.28 High High
opioid receptor 2 76.16 Quite High
Enkephalin 6 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the absence of DMSO, dynorphin B triggered GATA-4 and Nkx-2.5 gene expression and led to the appearance of both alpha-myosin heavy chain and myosin light chain-2V transcripts, two markers of cardiac differentiation.
dynorphin B Positive_regulation (triggered) of Gene_expression (expression) of Nkx-2.5 associated with dynorphin
1) Confidence 0.35 Published 2000 Journal Circ. Res. Section Abstract Doc Link 10926868 Disease Relevance 0 Pain Relevance 0.64
In the absence of DMSO, dynorphin B triggered GATA-4 and Nkx-2.5 gene expression and led to the appearance of both alpha-myosin heavy chain and myosin light chain-2V transcripts, two markers of cardiac differentiation.
dynorphin B Positive_regulation (triggered) of Gene_expression (expression) of Nkx-2.5 associated with dynorphin
2) Confidence 0.26 Published 2000 Journal Circ. Res. Section Abstract Doc Link 10926868 Disease Relevance 0 Pain Relevance 0.64

General Comments

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