INT89887

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Context Info
Confidence 0.32
First Reported 2000
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 0.80
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Gpx1) mitochondrion (Gpx1) oxidoreductase activity (Gpx1)
nucleus (Gpx1) lipid metabolic process (Gpx1) cytoplasm (Gpx1)
Anatomy Link Frequency
neuronal 2
endometrium 2
Gpx1 (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 11 98.88 Very High Very High Very High
ischemia 10 97.96 Very High Very High Very High
Pyramidal cell 1 69.84 Quite High
withdrawal 15 68.00 Quite High
Eae 1 57.84 Quite High
endometriosis 2 50.00 Quite Low
Dismenorea 2 50.00 Quite Low
Hippocampus 1 45.36 Quite Low
sSRI 1 41.00 Quite Low
qutenza 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 7 97.96 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 1 92.44 High High
Dysmenorrhea 2 76.48 Quite High
Endometriosis (extended) 2 75.84 Quite High
Stress 27 55.68 Quite High
Death 1 48.28 Quite Low
Disease 24 47.44 Quite Low
Toxicity 6 5.00 Very Low Very Low Very Low
Parkinson's Disease 3 5.00 Very Low Very Low Very Low
Hypoxia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, the expression of GPx1 (cytosolic GPx) is highly responsive to Se status.
Regulation (responsive) of Gene_expression (expression) of GPx1
1) Confidence 0.32 Published 2007 Journal International Journal of Biological Sciences Section Body Doc Link PMC1925139 Disease Relevance 0.06 Pain Relevance 0
The cell lysate was centrifuged for 10 min at 10,000 x g, the supernatant was collected for GSH and GPx assays.
Regulation (collected) of Gene_expression (assays) of GPx
2) Confidence 0.32 Published 2007 Journal International Journal of Biological Sciences Section Body Doc Link PMC1925139 Disease Relevance 0 Pain Relevance 0.03
On the other hand, the expression of GPx1 (cytosolic GPx) is highly responsive to Se status.
Regulation (responsive) of Gene_expression (expression) of GPx
3) Confidence 0.27 Published 2007 Journal International Journal of Biological Sciences Section Body Doc Link PMC1925139 Disease Relevance 0.06 Pain Relevance 0
RESULT(S): The analyses revealed phase-dependent changes of GPx expression in the surface and glandular epithelia in the eutopic endometrium during the menstrual cycle in the fertile controls, i.e., the expression was weak in the early proliferative phase, gradually increased, was most marked in the early secretory phase, and decreased thereafter.
Regulation (changes) of Gene_expression (expression) of GPx in endometrium
4) Confidence 0.23 Published 2000 Journal Fertil. Steril. Section Body Doc Link 10927050 Disease Relevance 0.15 Pain Relevance 0
In brief, treatment with fluoxetine protects neuronal damage after transient ischemia, and the neuroprotective effect of fluoxetine in an ischemic animal model may be related with the up-regulation of BDNF, CAT, GPX, and SOD1 expression.
Regulation (regulation) of Gene_expression (expression) of GPX in neuronal associated with ischemia and fluoxetine
5) Confidence 0.05 Published 2007 Journal Exp. Neurol. Section Abstract Doc Link 17328894 Disease Relevance 0.54 Pain Relevance 0.98

General Comments

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