INT9004

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Context Info
Confidence 0.40
First Reported 1992
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.05
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
Mast cells 2
Sema3e (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 1 100.00 Very High Very High Very High
Neuropeptide 2 95.20 Very High Very High Very High
bradykinin 1 92.72 High High
substance P 3 91.52 High High
Inflammatory response 1 86.72 High High
interstitial cystitis 4 85.44 High High
Pain 1 80.32 Quite High
Serotonin 2 68.96 Quite High
antagonist 1 33.68 Quite Low
Kinase C 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 100.00 Very High Very High Very High
Nociception 1 100.00 Very High Very High Very High
Hypersensitivity 2 99.74 Very High Very High Very High
Disease 1 87.76 High High
Pressure And Volume Under Development 1 86.40 High High
Interstitial Cystitis 4 85.44 High High
Enteropathy 1 82.56 Quite High
Immunization 1 45.44 Quite Low
Breast Cancer 1 30.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mast cells have been studied extensively for their involvement in allergic reactions, where they secrete numerous powerful mediators in response to immunoglobulin E and specific antigens.
Localization (secrete) of immunoglobulin E in Mast cells associated with hypersensitivity
1) Confidence 0.40 Published 1992 Journal Int. Arch. Allergy Immunol. Section Abstract Doc Link 1384869 Disease Relevance 0.44 Pain Relevance 0.23
PURPOSE: Mast cells are ubiquitous cells derived from the bone marrow and are responsible for allergic reactions as they release numerous vasodilatory, nociceptive and pro-inflammatory molecules in response to immunoglobulin E (IgE) and specific antigen.
Localization (release) of immunoglobulin E in Mast cells associated with nociception, inflammation and hypersensitivity
2) Confidence 0.08 Published 2000 Journal J. Urol. Section Abstract Doc Link 11061939 Disease Relevance 0.60 Pain Relevance 0.48

General Comments

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