INT90045

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Context Info
Confidence 0.19
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprd1) plasma membrane (Oprd1) cytoplasm (Oprd1)
signal transducer activity (Oprd1)
Oprd1 (Mus musculus)
P9Ehs1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 2 100.00 Very High Very High Very High
agonist 1 99.96 Very High Very High Very High
Antinociceptive 2 99.72 Very High Very High Very High
tail-flick 1 90.48 High High
Intracerebroventricular 1 81.60 Quite High
antinociception 2 75.00 Quite High
Opioid 1 75.00 Quite High
Enkephalin 1 72.40 Quite High
medulla 1 67.76 Quite High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Obesity 1 98.84 Very High Very High Very High
Diabetes Mellitus 7 98.60 Very High Very High Very High
Diabetes Mellitus-type I 2 95.52 Very High Very High Very High
Hyperglycemia 1 87.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The purpose of the present study was to evaluate antinociceptive response and G-protein activation by mu-opioid receptor and delta-opioid receptor agonists in the genetic non-obese diabetic (NOD) mouse, a model of type I insulin-dependent diabetes mellitus (IDDM).
delta-opioid receptor Positive_regulation (activation) of G-protein associated with diabetes mellitus-type i, diabetes mellitus, obesity, agonist, opioid receptor and antinociceptive
1) Confidence 0.19 Published 2000 Journal Eur. J. Pharmacol. Section Abstract Doc Link 10936496 Disease Relevance 0.92 Pain Relevance 0.64

General Comments

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