INT90090

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Context Info
Confidence 0.58
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.41
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ADO) oxidoreductase activity (ADO)
ADO (Homo sapiens)
Pain Link Frequency Relevance Heat
antinociception 1 100.00 Very High Very High Very High
adenocard 8 99.72 Very High Very High Very High
Opioid 1 80.48 Quite High
intrathecal 1 75.00 Quite High
Analgesic 1 75.00 Quite High
agonist 2 50.00 Quite Low
anesthesia 2 25.00 Low Low
Pain 2 10.00 Low Low
imagery 2 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteopetrosis 72 100.00 Very High Very High Very High
Malignant Neoplastic Disease 4 81.92 Quite High
Osteopoikilosis 6 75.44 Quite High
Growth Problems 4 70.56 Quite High
Hypocalcemia 2 67.28 Quite High
Convulsion 5 64.32 Quite High
Intellectual Impairment 2 57.20 Quite High
Cognitive Disorder 3 56.56 Quite High
Renal Tubular Acidosis 5 52.48 Quite High
Osteomyelitis 5 41.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The A(1)-AdoR agonists GW493838 and GR792363 are under evaluation for pain management.
Gene_expression (agonists) of AdoR
1) Confidence 0.58 Published 2008 Journal Expert Opin Investig Drugs Section Body Doc Link 19012505 Disease Relevance 0 Pain Relevance 0
BACKGROUND: Adenosine (Ado) is known, from studies in both animals and humans, to produce antinociception when administered systemically or intrathecally (IT).
Gene_expression (produce) of Ado associated with antinociception and adenocard
2) Confidence 0.47 Published 2000 Journal Acta Anaesthesiol Scand Section Abstract Doc Link 10939701 Disease Relevance 0 Pain Relevance 0.42
One hundred sixty-eight healthy subjects were scanned and divided into three groups: 55 adolescents (ADO, 13.2?
Gene_expression (13.2) of ADO
3) Confidence 0.14 Published 2010 Journal Frontiers in Systems Neuroscience Section Abstract Doc Link PMC2955419 Disease Relevance 0.06 Pain Relevance 0
The overall incidence of these conditions is difficult to estimate but autosomal recessive osteopetrosis (ARO) has an incidence of 1 in 250,000 births, and autosomal dominant osteopetrosis (ADO) has an incidence of 1 in 20,000 births.
Gene_expression (osteopetrosis) of ADO associated with osteopetrosis
4) Confidence 0.10 Published 2009 Journal Orphanet J Rare Dis Section Abstract Doc Link PMC2654865 Disease Relevance 1.36 Pain Relevance 0

General Comments

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