INT90177

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Context Info
Confidence 0.35
First Reported 2000
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.94
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

CPP (Homo sapiens)
Pain Link Frequency Relevance Heat
Nicotine 29 99.84 Very High Very High Very High
Cannabinoid 36 98.36 Very High Very High Very High
Morphine 17 98.28 Very High Very High Very High
cva 136 97.84 Very High Very High Very High
Dopamine 20 93.76 High High
Nucleus accumbens 3 91.76 High High
agonist 10 66.48 Quite High
antagonist 17 65.92 Quite High
addiction 29 62.88 Quite High
Endocannabinoid 42 61.44 Quite High
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 133 97.84 Very High Very High Very High
Nicotine Addiction 8 96.20 Very High Very High Very High
Recurrence 19 95.48 Very High Very High Very High
Brain Injury 26 87.84 High High
Cerebral Hypoxia 5 76.32 Quite High
Drug Dependence 17 62.88 Quite High
Coma 4 62.40 Quite High
Brain Death 1 61.20 Quite High
Injury 12 38.08 Quite Low
Emergencies 1 32.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
70 indicate there is a high probability of an acceptable CPP (CPP ?
Positive_regulation (acceptable) of Gene_expression (probability) of CPP
1) Confidence 0.35 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.62 Pain Relevance 0.46
We have previously shown that diazepam blocks both the formation and the expression of amphetamine-induced conditioned place preference (CPP), but has no effect on the CPP induced by morphine.
Positive_regulation (induced) of Gene_expression (expression) of CPP associated with morphine
2) Confidence 0.34 Published 2000 Journal Neuroreport Section Abstract Doc Link 10943721 Disease Relevance 0 Pain Relevance 0.42
Forget et al (2005) showed that SR141716A impaired both the establishment and the short-term expression of CPP induced by nicotine, suggesting that endogenous cannabinoids are implicated in nicotine’s motivational effects.
Positive_regulation (induced) of Gene_expression (expression) of CPP associated with cannabinoid and nicotine
3) Confidence 0.10 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656312 Disease Relevance 0.32 Pain Relevance 0.81

General Comments

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