INT90181

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 2000
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.08
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Hck) plasma membrane (Hck) cytoskeleton (Hck)
nucleus (Hck) kinase activity (Hck) lysosome (Hck)
Anatomy Link Frequency
bridges 1
Hck (Mus musculus)
Pain Link Frequency Relevance Heat
Analgesic 12 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Toxicity 1 82.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BmK I4 crystallized in the tetragonal space group I4, with unit-cell parameters a = b = 134.5, c = 60.6 A.
BmK Binding (crystallized) of
1) Confidence 0.36 Published 2000 Journal Acta Crystallogr. D Biol. Crystallogr. Section Abstract Doc Link 10944339 Disease Relevance 0.08 Pain Relevance 0.16
Accordingly, the functional surface of this region in Bj-xtrIT has also been reshaped in IT-AP, which implies subtle differences between BmK IT-AP and Bj-xtrIT in binding to the receptor, although most other critical residues for structure and function adopt almost identical conformations.
BmK Binding (binding) of
2) Confidence 0.03 Published 2005 Journal Acta Crystallogr. D Biol. Crystallogr. Section Abstract Doc Link 15608371 Disease Relevance 0 Pain Relevance 0.16
BmK IT-AP is an excitatory insect-specific beta-toxin with analgesic effect from the Chinese scorpion Buthus martensii Karsch (BmK) and consists of 72 residues cross-linked by four disulfide bridges.
BmK Binding (cross-linked) of in bridges associated with analgesic
3) Confidence 0.03 Published 2005 Journal Acta Crystallogr. D Biol. Crystallogr. Section Abstract Doc Link 15608371 Disease Relevance 0 Pain Relevance 0.17

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox