INT90347

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Context Info
Confidence 0.54
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.86
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gast)
Gast (Mus musculus)
Pain Link Frequency Relevance Heat
peptic ulcer disease 2 96.60 Very High Very High Very High
Inflammatory mediators 5 74.40 Quite High
Somatostatin 3 72.56 Quite High
Inflammation 15 66.32 Quite High
Inflammatory response 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 1 99.36 Very High Very High Very High
Helicobacter Infection 3 99.32 Very High Very High Very High
Infection 45 98.52 Very High Very High Very High
Stomach Cancer 5 96.96 Very High Very High Very High
Ulcers 2 96.60 Very High Very High Very High
Disease 3 96.08 Very High Very High Very High
Carcinoma 2 95.72 Very High Very High Very High
Targeted Disruption 1 90.76 High High
Apoptosis 8 89.44 High High
INFLAMMATION 23 74.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Other workers have also observed that Cox-2 inhibition influenced gastrin expression in an in vitro colorectal cancer model [34] and also in H. pylori positive gastric cancer patients [36].
Regulation (influenced) of Gene_expression (expression) of gastrin associated with colon cancer and stomach cancer
1) Confidence 0.54 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2667483 Disease Relevance 1.22 Pain Relevance 0.10
Altered gastrin expression associated with Helicobacter pylori infection may contribute to the pathogenesis of peptic ulcer disease or gastric cancer in man, but gastrin has not been investigated in a murine model of Helicobacter infection.
Regulation (Altered) of Gene_expression (expression) of gastrin associated with peptic ulcer disease, helicobacter infection, disease, stomach cancer and infection
2) Confidence 0.27 Published 2000 Journal Dig. Dis. Sci. Section Abstract Doc Link 10961708 Disease Relevance 0.64 Pain Relevance 0.16

General Comments

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