INT9040

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Context Info
Confidence 0.51
First Reported 1980
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 2.71
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CGB) small molecule metabolic process (CGB) extracellular region (CGB)
cellular nitrogen compound metabolic process (CGB) cell-cell signaling (CGB)
Anatomy Link Frequency
plasma 1
interstitial cells 1
CGB (Homo sapiens)
Pain Link Frequency Relevance Heat
narcan 11 100.00 Very High Very High Very High
Dopamine 3 99.98 Very High Very High Very High
opiate 1 98.44 Very High Very High Very High
antagonist 1 97.80 Very High Very High Very High
methotrexate 4 96.72 Very High Very High Very High
MU agonist 1 91.36 High High
opioid receptor 1 83.60 Quite High
Analgesic 2 77.24 Quite High
Inflammation 1 76.68 Quite High
abdominal pain 4 76.12 Quite High
Disease Link Frequency Relevance Heat
Ectopic Pregnancy 3 99.78 Very High Very High Very High
Diarrhoea 1 98.20 Very High Very High Very High
Vomiting 2 97.08 Very High Very High Very High
Reprotox - General 2 7 93.88 High High
Hemorrhage 2 93.84 High High
Tubal Pregnancy 5 92.76 High High
Reprotox - General 1 7 91.76 High High
Pain 1 81.84 Quite High
Emergencies 1 79.72 Quite High
INFLAMMATION 1 76.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fetal loss was diagnosed by decreasing beta-Human chorionic gonadotropin or pathology specimen.
Negative_regulation (decreasing) of chorionic gonadotropin
1) Confidence 0.51 Published 2008 Journal Ann Emerg Med Section Body Doc Link 18395935 Disease Relevance 0.24 Pain Relevance 0
RESULT(S): Expected decline in beta human chorionic gonadotropin (beta-hCG) levels without the need for any further intervention(s).
Negative_regulation (decline) of chorionic gonadotropin
2) Confidence 0.37 Published 2009 Journal Fertil. Steril. Section Body Doc Link 19819446 Disease Relevance 0.19 Pain Relevance 0
Expectant management is appropriate only when beta subunit of human chorionic gonadotropin levels are low and declining.
Negative_regulation (declining) of chorionic gonadotropin
3) Confidence 0.34 Published 2005 Journal Am Fam Physician Section Abstract Doc Link 16300032 Disease Relevance 0.77 Pain Relevance 0.11
In 9 cases treated with PG, the method proved to be successful in 89%, as indicated by reduction of human chorionic gonadotropin (hCG) serum values to less than 20 IU/l.
Negative_regulation (reduction) of chorionic gonadotropin
4) Confidence 0.32 Published 1992 Journal Cesk Gynekol Section Abstract Doc Link 1385760 Disease Relevance 0.24 Pain Relevance 0.08
Both plasma progesterone values and human chorionic gonadotropin (hCG) beta-subunit levels declined during the 10-hour observation period.
Negative_regulation (declined) of chorionic gonadotropin in plasma
5) Confidence 0.27 Published 1984 Journal Am. J. Obstet. Gynecol. Section Abstract Doc Link 6507528 Disease Relevance 0.75 Pain Relevance 0.06
Expectant management of suspected ectopic pregnancies even with rising beta-subunit human chorionic gonadotropin levels.
Negative_regulation (rising) of chorionic gonadotropin associated with ectopic pregnancy
6) Confidence 0.20 Published 1994 Journal Arch. Gynecol. Obstet. Section Title Doc Link 7526807 Disease Relevance 0.43 Pain Relevance 0.08
Dopamine inhibits the naloxone induced gonadotrophin rise in man.
Negative_regulation (inhibits) of gonadotrophin associated with dopamine and narcan
7) Confidence 0.09 Published 1980 Journal Clin. Endocrinol. (Oxf) Section Title Doc Link 6784978 Disease Relevance 0 Pain Relevance 0.57
The enzymatically dispersed rat testicular interstitial cells were incubated with S-petasin (0-4.3 x 10(-5)M) in the presence or absence of human chorionic gonadotropin (hCG, 0.05 IU/ml), forskolin (adenylyl cyclase activator, 10(-5) M), and androstenedione (testosterone biosynthesis precursor, 10(-9) M) at 34 degrees C for 1 h.
Negative_regulation (absence) of chorionic gonadotropin in interstitial cells
8) Confidence 0.02 Published 2000 Journal Chin J Physiol Section Abstract Doc Link 11132091 Disease Relevance 0.08 Pain Relevance 0.12
This stimulatory effect of the gonadotrophin was inhibited by the highest dose of P4 (10(-5) M).
Negative_regulation (inhibited) of gonadotrophin
9) Confidence 0.00 Published 2000 Journal Reprod. Nutr. Dev. Section Abstract Doc Link 10737551 Disease Relevance 0 Pain Relevance 0.29

General Comments

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