INT90416

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Context Info
Confidence 0.67
First Reported 2000
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.58
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RASA1) signal transduction (RASA1) plasma membrane (RASA1)
embryo development (RASA1) cytoplasm (RASA1)
RASA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
TRP channel 1 95.60 Very High Very High Very High
agonist 2 94.48 High High
Inflammation 2 84.64 Quite High
Pain 2 83.52 Quite High
Glutamate 1 77.40 Quite High
medulla 1 77.20 Quite High
cva 5 71.20 Quite High
gABA 3 67.44 Quite High
GABAergic 1 58.40 Quite High
Hippocampus 2 52.48 Quite High
Disease Link Frequency Relevance Heat
Arterial-venous Cerebral Malformations 11 100.00 Very High Very High Very High
Brain Hemorrhage 2 98.28 Very High Very High Very High
Esophageal Varices 1 96.36 Very High Very High Very High
Ulcers 4 94.72 High High
Hemorrhage 21 94.16 High High
Emergencies 5 92.88 High High
INFLAMMATION 2 84.64 Quite High
Pain 1 83.52 Quite High
Anaemia 5 83.28 Quite High
Cv General 3 Under Development 4 54.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One possible mechanism for this effect is via an increase in gap junction proteins, as olivary cells are electrotonically coupled.
Positive_regulation (increase) of gap
1) Confidence 0.67 Published 2000 Journal Novartis Found. Symp. Section Abstract Doc Link 10965507 Disease Relevance 0 Pain Relevance 0.17
YP uptake was not inhibited by a panel of putative gap junction/pannexin blockers, suggesting that gap junction proteins are not required in this process.
Neg (not) Positive_regulation (required) of gap
2) Confidence 0.49 Published 2010 Journal Am. J. Physiol., Cell Physiol. Section Abstract Doc Link 20457836 Disease Relevance 0.17 Pain Relevance 0.33
With increasing availability of endoscopy and elective angiography AVM is being more frequently recognized.
Positive_regulation (increasing) of AVM associated with arterial-venous cerebral malformations
3) Confidence 0.01 Published 2009 Journal World J Emerg Surg Section Body Doc Link PMC2687422 Disease Relevance 1.41 Pain Relevance 0.06

General Comments

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