INT90474

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Context Info
Confidence 0.42
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.06

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generation of precursor metabolites and energy (ADRB3) aging (ADRB3) plasma membrane (ADRB3)
nucleus (ADRB3) carbohydrate metabolic process (ADRB3) signal transducer activity (ADRB3)
ADRB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 66.84 Quite High
Potency 1 52.36 Quite High
agonist 2 49.56 Quite Low
anesthesia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Overactive Bladder 4 99.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present functional study provides the first evidence that relaxation of the ferret detrusor by beta-adrenoceptor activation is mediated mainly via the beta(3)-adrenoceptor, as in the human detrusor.
Positive_regulation (mediated) of Positive_regulation (activation) of beta-adrenoceptor associated with overactive bladder
1) Confidence 0.42 Published 2000 Journal Eur. J. Pharmacol. Section Abstract Doc Link 10969156 Disease Relevance 0.25 Pain Relevance 0.06

General Comments

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